The role of B cells in COVID-19 infection and vaccination

被引：58

作者：

Chen, Shiru ^{[1
,2
]}

Guan, Fei ^{[1
]}

Candotti, Fabio ^{[3
]}

Benlagha, Kamel ^{[4
]}

Camara, Niels Olsen Saraiva ^{[5
]}

Herrada, Andres A. ^{[6
]}

James, Louisa K. ^{[7
]}

Lei, Jiahui ^{[1
]}

Miller, Heather ^{[8
]}

Kubo, Masato ^{[9
]}

Ning, Qin ^{[10
]}

Liu, Chaohong ^{[1
]}

机构：

[1] Huazhong Univ Sci Technol, Tongji Med Coll, Sch Basic Med, Dept Pathogen Biol, Wuhan, Peoples R China

[2] Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Internal Med, Div Gastroenterol & Hepatol, Wuhan, Peoples R China

[3] Univ Lausanne, Lausanne Univ Hosp, Div Immunol & Allergy, Lausanne, Switzerland

[4] Univ Paris, Inst Rech St Louis, Paris, France

[5] Univ Sao Paulo, Inst Biomed Sci, Dept Immunol, Lab Human Immunol, Sao Paulo, SP, Brazil

[6] Univ Autonoma Chile, Fac Ciencias Salud, Inst Ciencias Biomed, Lymphat & Inflammat Res Lab, Talca, Chile

[7] Queen Mary Univ London, Bizard Inst, Ctr Immunobiol, London, England

[8] Cytek Biosci, R&D Clin Reagents, Fremont, CA USA

[9] Inst Phys & Chem Res RIKEN, Yokohama Inst, Ctr Integrat Med Sci IMS, Lab Cytokine Regulat, Yokohama, Kanagawa, Japan

[10] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Infect Dis, Wuhan, Peoples R China

来源：

FRONTIERS IN IMMUNOLOGY | 2022年 / 13卷

关键词：

B cells; antibody; COVID-19; SARS-CoV-2; memory B cells; vaccination; NEUTROPHIL EXTRACELLULAR TRAPS; ACUTE RESPIRATORY SYNDROME; GERMINAL-CENTERS; SARS-COV-2; INFECTION; MARGINAL ZONE; MEMORY; ANTIBODY; RESPONSES; IMMUNITY; HYPERMUTATION;

D O I：

10.3389/fimmu.2022.988536

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

B cells secrete antibodies and mediate the humoral immune response, making them extremely important in protective immunity against SARS-CoV-2, which caused the coronavirus disease 2019 (COVID-19) pandemic. In this review, we summarize the positive function and pathological response of B cells in SARS-CoV-2 infection and re-infection. Then, we structure the immunity responses that B cells mediated in peripheral tissues. Furthermore, we discuss the role of B cells during vaccination including the effectiveness of antibodies and memory B cells, viral evolution mechanisms, and future vaccine development. This review might help medical workers and researchers to have a better understanding of the interaction between B cells and SARS-CoV-2 and broaden their vision for future investigations.

引用

页数：13

共 165 条

[31] Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection [J].

Dan, Jennifer M. ;

Mateus, Jose ;

Kato, Yu ;

Hastie, Kathryn M. ;

Yu, Esther Dawen ;

Faliti, Caterina E. ;

Grifoni, Alba ;

Ramirez, Sydney, I ;

Haupt, Sonya ;

Frazier, April ;

Nakao, Catherine ;

Rayaprolu, Vamseedhar ;

Rawlings, Stephen A. ;

Peters, Bjoern ;

Krammer, Florian ;

Simon, Viviana ;

Saphire, Erica Ollmann ;

Smith, Davey M. ;

Weiskopf, Daniela ;

Sette, Alessandro ;

Crotty, Shane .

SCIENCE, 2021, 371 (6529) :587-+

[32] Transient monoarthritis and psoriatic skin lesions following COVID-19 [J].

De Stefano, Ludovico ;

Rossi, Silvia ;

Montecucco, Carlomaurizio ;

Bugatti, Serena .

ANNALS OF THE RHEUMATIC DISEASES, 2023, 82 (04)

[33] SARS and MERS: recent insights into emerging coronaviruses [J].

de Wit, Emmie ;

van Doremalen, Neeltje ;

Falzarano, Darryl ;

Munster, Vincent J. .

NATURE REVIEWS MICROBIOLOGY, 2016, 14 (08) :523-534

[34] Seasonal coronavirus protective immunity is short-lasting [J].

Edridge, Arthur W. D. ;

Kaczorowska, Joanna ;

Hoste, Alexis C. R. ;

Bakker, Margreet ;

Klein, Michelle ;

Loens, Katherine ;

Jebbink, Maarten F. ;

Matser, Amy ;

Kinsella, Cormac M. ;

Rueda, Paloma ;

Ieven, Margareta ;

Goossens, Herman ;

Prins, Maria ;

Sastre, Patricia ;

Deijs, Martin ;

van der Hoek, Lia .

NATURE MEDICINE, 2020, 26 (11) :1691-+

[35] Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA [J].

Ferron, Francois ;

Subissi, Lorenzo ;

De Morais, Ana Theresa Silveira ;

Nhung Thi Tuyet Le ;

Sevajol, Marion ;

Gluais, Laure ;

Decroly, Etienne ;

Vonrhein, Clemens ;

Bricogne, Gerard ;

Canard, Bruno ;

Imbert, Isabelle .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (02) :E162-E171

[36]

Fleites Yoel A, 2021, Euroasian J Hepatogastroenterol, V11, P59, DOI 10.5005/jp-journals-10018-1344

[37]

Gaebler C, 2021, NATURE, V591, P639, DOI [10.1038/s41586-021-03207-w, 10.1101/2020.11.03.367391]

[38]

Garcia-Beltran WF, 2021, CELL, V184, P2372, DOI [10.1016/j.cell.2021.03.013, 10.1016/j.cell.2021.04.006, 10.1101/2021.02.14.21251704]

[39]

Garcia-Sastre A., 2021, MEDRXIV, DOI DOI 10.1101/2021.01.26.21250543

[40] Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus-infected mice [J].

GeurtsvanKessel, Corine H. ;

Willart, Monique A. M. ;

Bergen, Ingrid M. ;

van Rijt, Leonie S. ;

Muskens, Femke ;

Elewaut, Dirk ;

Osterhaus, Albert D. M. E. ;

Hendriks, Rudi ;

Rimmelzwaan, Guus F. ;

Lambrecht, Bart N. .

JOURNAL OF EXPERIMENTAL MEDICINE, 2009, 206 (11) :2339-2349

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