A "turn-on'' carbon nanotube-Ag nanoclusters fluorescent sensor for sensitive and selective detection of Hg2+ with cyclic amplification of exonuclease III activity

被引:85
作者
Wang, Guangfeng [1 ,2 ,3 ,4 ]
Xu, Gang [1 ,2 ,3 ,4 ]
Zhu, Yanhong [1 ,2 ,3 ,4 ]
Zhang, Xiaojun [1 ,2 ,3 ,4 ]
机构
[1] Key Lab Chembiosensing, Wuhan 241000, Anhui, Peoples R China
[2] Key Lab Funct Mol Solids, Wuhu 241000, Anhui, Peoples R China
[3] Anhui Normal Univ, Coll Chem & Mat Sci, Wuhu 241000, Peoples R China
[4] Anhui Normal Univ, Ctr Nanosci & Nanotechnol, Wuhu 241000, Peoples R China
基金
中国国家自然科学基金;
关键词
DNA DETECTION; SIGNAL AMPLIFICATION; ENERGY-TRANSFER; BASE-PAIRS; GOLD; BIOSENSOR; NANOPARTICLES;
D O I
10.1039/c3cc46716c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
With exonuclease III activity on DNA hybrids containing thymine-Hg2+-thymine, a label-free ultrasensitive "turn-on'' fluorescent sensor involving "quenching'' and "reappearing'' processes based on a carbon nanotube-Ag nanoclusters system is demonstrated for amplified determination of Hg2+.
引用
收藏
页码:747 / 750
页数:4
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