QT prolongation with hydroxychloroquine and azithromycin for the treatment of COVID-19: The need for pharmacogenetic insights

被引:2
作者
Lopez-Medina, Ana I. [1 ]
Campos-Staffico, Alessandra M. [1 ]
Luzum, Jasmine A. [1 ]
机构
[1] Univ Michigan, Coll Pharm, Dept Clin Pharm, 428 Church St, Ann Arbor, MI 48109 USA
关键词
arrhythmia; azithromycin; COVID-19; hydroxychloroquine; ion channels; pharmacogenetics; polymorphism; QT prolongation;
D O I
10.1111/jce.14722
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2793 / 2794
页数:2
相关论文
共 50 条
  • [21] HYDROXYCHLOROQUINE AND AZITHROMYCIN COMBINATION COULD BE LETHAL TO COVID-19 PATIENTS
    Mohammad, Firdous Sayeed
    Karmakar, Varnita
    Irfan, Zainab
    FARMACIA, 2020, 68 (03) : 384 - 389
  • [22] Evaluation of Corrected QT Intervals of 74 COVID-19 Patients Treated with Hydroxychloroquine in Combination with or without Azithromycin and/or Favipiravir
    Uyaroglu, Oguz Abdullah
    Sener, Yusuf Ziya
    Ozdede, Murat
    Basaran, Nursel Calik
    Ozisik, Lale
    Sahin, Taha Koray
    Canpolat, Ugur
    Inkaya, Ahmet Cagkan
    Yorgun, Hikmet
    Guven, Gulay Sain
    Aytemir, Kudret
    EUROPEAN JOURNAL OF THERAPEUTICS, 2021, 27 (04): : 311 - 317
  • [23] Hydroxychloroquine/azithromycin in COVID-19: The association between time to treatment and case fatality rate
    Alfonso Accinelli, Roberto
    Jesus Ynga-Melendez, Grisel
    Alonso Leon-Abarca, Juan
    Marianella Lopez, Lidia
    Carlos Madrid-Cisneros, Juan
    Diego Mendoza-Saldana, Juan
    TRAVEL MEDICINE AND INFECTIOUS DISEASE, 2021, 44
  • [24] Safety signals for QT prolongation or Torsades de Pointes associated with azithromycin with or without chloroquine or hydroxychloroquine
    Sarayani, Amir
    Cicali, Brian
    Henriksen, Carl H.
    Brown, Joshua D.
    RESEARCH IN SOCIAL & ADMINISTRATIVE PHARMACY, 2021, 17 (02) : 483 - 486
  • [25] Impact of Azithromycin and/or Hydroxychloroquine on Hospital Mortality in COVID-19
    Albani, Filippo
    Fusina, Federica
    Giovannini, Alessia
    Ferretti, Pierluigi
    Granato, Anna
    Prezioso, Chiara
    Divizia, Danilo
    Sabaini, Alessandra
    Marri, Marco
    Malpetti, Elena
    Natalini, Giuseppe
    JOURNAL OF CLINICAL MEDICINE, 2020, 9 (09) : 1 - 10
  • [26] Azithromycin in the treatment of COVID-19: a review
    Echeverria-Esnal, Daniel
    Martin-Ontiyuelo, Clara
    Navarrete-Rouco, Maria Eugenia
    De-Antonio Cusco, Marta
    Ferrandez, Olivia
    Horcajada, Juan Pablo
    Grau, Santiago
    EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 2021, 19 (02) : 147 - 163
  • [27] Prevention and treatment of COVID-19: Focus on interferons, chloroquine/hydroxychloroquine, azithromycin, and vaccine
    Bakadia, Bianza Moise
    He, Feng
    Souho, Tiatou
    Lamboni, Lallepak
    Ullah, Muhammad Wajid
    Boni, Biaou Ode
    Ahmed, Abeer Ahmed Qaed
    Mukole, Biampata Mutu
    Yang, Guang
    BIOMEDICINE & PHARMACOTHERAPY, 2021, 133
  • [28] QTc Prolongation Risk Evaluation in Female COVID-19 Patients Undergoing Chloroquine and Hydroxychloroquine With/Without Azithromycin Treatment
    Grewal, Sarah
    Jankelson, Lior
    van den Broek, Marcel P. H.
    Cour, Martin
    Bachmann, Gloria
    Kostis, John B.
    Misra, Kamana
    FRONTIERS IN CARDIOVASCULAR MEDICINE, 2020, 7
  • [29] Hydroxychloroquine and Azithromycin to Treat Patients With COVID-19: Both Friends and Foes?
    Megarbane, Bruno
    Scherrmann, Jean-Michel
    JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 60 (07) : 808 - 814
  • [30] Acute Respiratory Failure Secondary to COVID-19 Viral Pneumonia Managed With Hydroxychloroquine/Azithromycin Treatment
    Ng, Kenneth K.
    Ng, Mitchell K.
    Zhyvotovska, Angelina
    Singh, Sahib
    Shevde, Ketan
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2020, 12 (05)