A simple ductal mammary papilloma in a male maned wolf (Chrysocyon brachyurus)

被引：6

作者：

Cassali, Geovanni D. ^{[1
]}

Bertagnolli, Angelica C. ^{[1
]}

Ferreira, Enio ^{[1
]}

Malta, Marcelo C. C. ^{[2
]}

机构：

[1] Univ Fed Minas Gerais, Lab Comparat Pathol, Dept Gen Pathol, Inst Biol Sci, BR-31270901 Belo Horizonte, MG, Brazil

[2] Zoo Bot Fdn, Belo Horizonte, MG, Brazil

来源：

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION | 2009年 / 21卷 / 01期

关键词：

Chrysocyon brachyurus; ductal mammary papilloma; male maned wolves; BREAST-CANCER; RISK-FACTORS; GLAND; MEN; ESTROGEN; MARKER; TUMORS; P63;

D O I：

10.1177/104063870902100127

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

A 1-cm-diameter nodule was identified in the left inguinal mammary gland of a 9-year-old male maned wolf (Chrysocyon bruchyurus). The mass was surgically excised and examined histologically. Microscopically, the neoplasm consisted of papillary proliferations of epithelial cells on well-defined fibrovascular stalks. A myoepithelial layer was located between the single layer of epithelial cells and the fibrovascular stalk. This histologic appearance was compatible with a diagnosis of simple ductal mammary papilloma. Irnmunohistochemical staining was positive for p63, cytokeratins AEI/AE3, and estrogen receptors. The clinical and histologic observations in the present case indicate that male maned wolves may develop mammary tumors that are similar to those observed in domestic dogs and humans.

引用

页码：153 / 155

页数：3

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