Isoenzymatic polymorphism of Leishmania infantum in southern Spain

被引：40
作者：
Martin-Sanchez, J
Gramiccia, M
Di Muccio, T
Ludovisi, A
Morillas-Márquez, F
机构：
[1] Univ Granada, Fac Farm, Dept Parasitol, E-18071 Granada, Spain
[2] Ist Super Sanita, Lab Parassitol, I-00161 Rome, Italy
来源：
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2004年 / 98卷 / 04期
关键词：
Leishmania infantum; zymodemes; polymorphism; hosts; vectors; Spain;
D O I：
10.1016/S0035-9203(03)00060-9
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Over a period of more than 10 years we have isolated and classified. 161 Leishmania strains from cases of human visceral, cutaneous and mucosal leishmaniasis in immunocompetent subjects, from cases of visceral leishmaniasis in immunocompromised individuals with HIV, from dogs with leishmaniasis (visceral and cutaneous), from Rattus rattus and from sandflies. The strains were all L. infantum, the only species endemic in Spain, and corresponded to 20 different zymodemes. We describe the life cycle of these zymodemes for which, in most cases, we only partially know the hosts involved. We also discuss possible reasons for the greater polymorphism of L. infantum in southern Spain. (C) 2003 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
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收藏
页码：228 / 232
页数：5
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