Isoenzymatic polymorphism of Leishmania infantum in southern Spain

被引：40
作者：
Martin-Sanchez, J
Gramiccia, M
Di Muccio, T
Ludovisi, A
Morillas-Márquez, F
机构：
[1] Univ Granada, Fac Farm, Dept Parasitol, E-18071 Granada, Spain
[2] Ist Super Sanita, Lab Parassitol, I-00161 Rome, Italy
来源：
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2004年 / 98卷 / 04期
关键词：
Leishmania infantum; zymodemes; polymorphism; hosts; vectors; Spain;
D O I：
10.1016/S0035-9203(03)00060-9
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Over a period of more than 10 years we have isolated and classified. 161 Leishmania strains from cases of human visceral, cutaneous and mucosal leishmaniasis in immunocompetent subjects, from cases of visceral leishmaniasis in immunocompromised individuals with HIV, from dogs with leishmaniasis (visceral and cutaneous), from Rattus rattus and from sandflies. The strains were all L. infantum, the only species endemic in Spain, and corresponded to 20 different zymodemes. We describe the life cycle of these zymodemes for which, in most cases, we only partially know the hosts involved. We also discuss possible reasons for the greater polymorphism of L. infantum in southern Spain. (C) 2003 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
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收藏
页码：228 / 232
页数：5
相关论文
共 27 条
[1]  
ACEDOSANCHEZ C, 1996, INT J PARASITOL, V25, P303
[2]   AIDS and Leishmania infantum - New approaches for new epidemiological problem [J].
Alvar, J ;
GutierrezSolar, B ;
Pachon, I ;
Calbacho, E ;
Ramirez, M ;
Valles, R ;
Guillen, JL ;
Canavate, C ;
Amela, C .
CLINICS IN DERMATOLOGY, 1996, 14 (05) :541-546
[3]   Evidence for hybridization by multilocus enzyme electrophoresis and random amplified polymorphic DNA between Leishmania braziliensis and Leishmania panamensis/guyanensis in Ecuador [J].
Banuls, AL ;
Guerrini, F ;
LePont, F ;
Barrera, C ;
Espinel, I ;
Guderian, R ;
Echeverria, R ;
Tibayrenc, M .
JOURNAL OF EUKARYOTIC MICROBIOLOGY, 1997, 44 (05) :408-411
[4]  
BANULS AL, 2002, T R SOC TROP MED HYG, V96, P13
[5]  
Benikhlef R, 2001, B SOC PATHOL EXOT, V94, P14
[6]   Is Leishmania infantum zymodeme MON-253 involved in an outbreak among intravenous drug users? [J].
Chicharro, C ;
Sirera, G ;
Ares, M ;
Sans, A ;
Videla, S ;
Alvar, J .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1999, 93 (04) :385-386
[7]  
DESJEUX P, 1991, INFORMATION EPIDEMIO
[8]  
Evans D.A., 1987, Parassitologia (Rome), V29, P165
[9]  
Fernandez Martinez F., 1913, ACTUAL MED, V3, P82
[10]   The life-cycle of Leishmania infantum MON-77 in the Priorat (Catalonia, Spain) involves humans, dogs and sandflies;: also literature review of distribution and hosts of L-infantum zymodemes in the Old World [J].
Gállego, M ;
Pratlong, F ;
Fisa, R ;
Riera, C ;
Rioux, JA ;
Dedet, JP ;
Portús, M .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2001, 95 (03) :269-271
123