Dynamics of Specific Vesicle-Substrate Adhesion: From Local Events to Global Dynamics

被引：53

作者：

Reister-Gottfried, Ellen ^{[1
]}

Sengupta, Kheya ^{[2
]}

Lorz, Barbara ^{[3
]}

Sackmann, Erich ^{[3
]}

Seifert, Udo ^{[1
]}

Smith, Ana-Suncana ^{[1
]}

机构：

[1] Univ Stuttgart, Inst Theoret Phys 2, D-70550 Stuttgart, Germany

[2] CINaM CNRS, UPR3118, Marseille 9, France

[3] Tech Univ Munich, Inst Biophys E22, D-85748 Garching, Germany

来源：

PHYSICAL REVIEW LETTERS | 2008年 / 101卷 / 20期

关键词：

D O I：

10.1103/PhysRevLett.101.208103

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We present a synergistic combination of simulations and experimental data on the dynamics of membrane adhesion. We show that a change in either the density or the strength of the bonds results in very different dynamics. Such behavior is explained by introducing an effective binding affinity that emerges as a result of the competition between the strength of the chemical bonds and the environment defined by the fluctuating membrane.

引用

页数：4

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