Graphene oxide-photosensitizer conjugate as a redox-responsive theranostic agent

被引：87

作者：

Cho, Youngnam ^{[1
,2
]}

Choi, Yongdoo ^{[1
]}

机构：

[1] Natl Canc Ctr, Mol Imaging & Therapy Branch, Goyang Si 410769, Gyeonggi Do, South Korea

[2] Purdue Univ, Ctr Paralysis Res, Dept Basic Med Sci, W Lafayette, IN 47907 USA

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 79期

关键词：

DRUG-DELIVERY; THERAPY;

D O I：

10.1039/c2cc35197h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A nano-sized graphene oxide-photosensitizer conjugate with a redox-responsive cleavable disulfide linker is non-fluorescent and non-phototoxic, even upon light irradiation. It becomes highly fluorescent and phototoxic inside cancer cells, where glutathione is used as an initiator for activating the photosensitizer.

引用

页码：9912 / 9914

页数：3

共 14 条

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