Pediatric Primary Anaplastic Ganglioglioma: A Case Report and Review of the Literature

被引：11

作者：

Scoccianti, Silvia ^{[1
]}

Giordano, Flavio

Agresti, Benedetta ^{[1
]}

Detti, Beatrice ^{[1
]}

Cipressi, Samantha ^{[1
]}

Franceschini, Davide ^{[1
]}

Greto, Daniela ^{[1
]}

Mussa, Federico

Sardi, Iacopo ^{[2
]}

Buccoliero, Annamaria ^{[3
]}

Arico, Maurizio ^{[2
]}

Genitori, Lorenzo

Biti, Giampaolo ^{[1
]}

机构：

[1] Azienda Osped Univ Careggi, Radiat Oncol Unit, IT-50134 Florence, Italy

[2] Anna Meyer Childrens Hosp, Pediat OncoHematol Unit, Florence, Italy

[3] Anna Meyer Childrens Hosp, Pathol Unit, Florence, Italy

来源：

PEDIATRIC NEUROSURGERY | 2012年 / 48卷 / 01期

关键词：

Anaplastic ganglioglioma; Radiotherapy; Chemotherapy; POSTOPERATIVE RADIOTHERAPY; RECURRENCE; FEATURES; TUMORS;

D O I：

10.1159/000340067

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Gangliogliomas with anaplastic features are classified as grade III tumors by the World Health Organization. The clinical course and optimal treatment of anaplastic gangliogliomas have not been well understood to date. We report a case of a primary pure anaplastic ganglioglioma in a 14-year-old male treated with surgery and radiotherapy, who is disease-free 6 years after the diagnosis. A review of primary pure anaplastic gangliogliomas in children (between 3 and 21 years of age) is presented. Gross total removal and focal radiotherapy with a total dose of 54 Gy are recommended. The addition of chemotherapy should be evaluated. Prospective studies are needed to identify an appropriate chemotherapy schedule and to define biological factors in order to select those patients with a poor prognosis, who are to be treated with a more aggressive therapy. Copyright (c) 2012 S. Karger AG, Basel

引用

页码：35 / 41

页数：7

共 29 条

[1]

Blümcke I, 2002, J NEUROPATH EXP NEUR, V61, P575

[2]

CAMPOS MG, 1994, NEUROL RES, V16, P317

[3] Mixed neuronal-glial tumors (gangliogliomas) in children [J].

Chintagumpala, MM ;

Armstrong, D ;

Miki, S ;

Nelson, T ;

Cheek, W ;

Laurent, J ;

Mahoney, DH .

PEDIATRIC NEUROSURGERY, 1996, 24 (06) :306-313

[4] Malignant ganglioglioma: case report and review of literature [J].

DeMarchi, Ryan ;

Abu-Abed, Suzy ;

Munoz, David ;

Macdonald, R. Loch .

JOURNAL OF NEURO-ONCOLOGY, 2011, 101 (02) :311-318

[5] GANGLIOGLIOMA - 13 YEARS OF EXPERIENCE [J].

HADDAD, SF ;

MOORE, SA ;

MENEZES, AH ;

VANGILDER, JC .

NEUROSURGERY, 1992, 31 (02) :171-178

[6] ANAPLASTIC GANGLIOGLIOMA OF THE BRAIN-STEM DEMONSTRATING ACTIVE NEUROSECRETORY FEATURES OF NEOPLASTIC NEURONAL CELLS [J].

HIROSE, T ;

KANNUKI, S ;

NISHIDA, K ;

MATSUMOTO, K ;

SANO, T ;

HIZAWA, K .

ACTA NEUROPATHOLOGICA, 1992, 83 (04) :365-370

[7] Intracranial ganglioglioma: preoperative characteristics and oncologic outcome after surgery [J].

Im, SH ;

Chung, CK ;

Cho, BK ;

Wang, KC ;

Yu, IK ;

Song, IC ;

Cheon, GJ ;

Lee, DS ;

Kim, NR ;

Chi, JG .

JOURNAL OF NEURO-ONCOLOGY, 2002, 59 (02) :173-183

[8]

Isimbaldi G, 1996, CLIN NEUROPATHOL, V15, P192

[9] Anaplastic ganglioglioma in a middle-aged woman: A case report with a review of the literature [J].

Kang, Dong-Ho ;

Lee, Chu-Hee ;

Hwang, Soo-Hyun ;

Park, In-Sung ;

Han, Jong-Woo ;

Jung, Jin-Myung .

JOURNAL OF KOREAN MEDICAL SCIENCE, 2007, 22 :S139-S144

[10] Anaplastic ganglioglioma in children [J].

Karremann, Michael ;

Pietsch, Torsten ;

Janssen, Gisela ;

Kramm, Christof M. ;

Wolff, Johannes E. A. .

JOURNAL OF NEURO-ONCOLOGY, 2009, 92 (02) :157-163

← 1 2 3 →