A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs

被引：16
|
作者：
Jang, Sung Wan [1 ]
Suh, Won Se [1 ]
Kim, Chung Sub [1 ]
Kim, Ki Hyun [1 ]
Lee, Kang Ro [1 ]
机构：
[1] Sungkyunkwan Univ, Sch Pharm, Nat Prod Lab, Suwon 440746, South Korea
来源：
ARCHIVES OF PHARMACAL RESEARCH | 2015年 / 38卷 / 11期
基金：
新加坡国家研究基金会;
关键词：
Spiraea prunifolia var. simpliciflora; Phenolic glycoside; Cytotoxicity; LIGNAN GLYCOSIDE; PRUNIOSIDE-A; CONSTITUENTS; CAFFEOYL; DERIVATIVES; LEAVES;
D O I：
10.1007/s12272-015-0610-y
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The phytochemical investigation of the methanol extract from the twigs of Spiraea prunifolia var. simpliciflora (Rosaceae) using column chromatography led to the isolation of a new phenol glycoside, 1-O-(E)-caffeoyl-2-O-p-(E)-coumaroyl-beta-d-glucopyranose (1), together with 16 known phenolic compounds (2-17). The structure of this new compound was elucidated by analysis of spectroscopic data including 1D, 2D nuclear magnetic resonance and HR-FAB-MS data. The isolated compounds were tested for cytotoxicity against four human tumor cell lines in vitro using the sulforhodamine B bioassay.
引用
收藏
页码：1943 / 1951
页数：9
相关论文
共 50 条
  • [1] A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs
    Sung Wan Jang
    Won Se Suh
    Chung Sub Kim
    Ki Hyun Kim
    Kang Ro Lee
    Archives of Pharmacal Research, 2015, 38 : 1943 - 1951
  • [2] PHENYLGLYCOSIDES FROM THE STEMS OF Spiraea prunifolia var. simpliciflora
    Kim, Su-Yeon
    Song, Na-Young
    Cho, Jin-Gyeong
    Kwon, Jeong-Hwa
    Song, Myoung-Chong
    Ahn, Eun Mi
    Kang, Hee Cheol
    Baek, Nam-In
    CHEMISTRY OF NATURAL COMPOUNDS, 2015, 51 (05) : 873 - 876
  • [3] Phenylglycosides from the Stems of Spiraea prunifolia var. simpliciflora
    Su-Yeon Kim
    Na-Young Song
    Jin-Gyeong Cho
    Jeong-Hwa Kwon
    Myoung-Chong Song
    Eun Mi Ahn
    Hee Cheol Kang
    Nam-In Baek
    Chemistry of Natural Compounds, 2015, 51 : 873 - 876
  • [4] A New Megastigmane Glucoside and Three New Flavonoid Glycosides from Spiraea prunifolia var. simpliciflora
    Yean, Min Hye
    Kim, Ju Sun
    Kang, Sam Sik
    Kim, Yeong Shik
    HELVETICA CHIMICA ACTA, 2014, 97 (08) : 1123 - 1131
  • [5] Investigation of chemical constituents from Spiraea prunifolia var. simpliciflora and their biological activities
    Kim, Chung Sub
    Oh, Joonseok
    Suh, Won Se
    Jang, Sung Wan
    Subedi, Lalita
    Kim, Sun Yeou
    Choi, Sang Un
    Lee, Kang Ro
    PHYTOCHEMISTRY LETTERS, 2017, 22 : 255 - 260
  • [6] Antioxidant and Anti-Inflammatory Effects of Spiraea prunifolia var. simpliciflora Extract
    Kim, Ji Eun
    Bae, Su Mi
    Bae, Eun Young
    Ly, Sun Yung
    ANNALS OF NUTRITION AND METABOLISM, 2019, 75 : 290 - 291
  • [7] Assessment of the influence of urban stormwater runoff on the growth of Spiraea prunifolia var. simpliciflora
    Choi, Hyeseon
    Geronimo, Franz Kevin
    Hong, Jungsun
    Kim, Lee-Hyung
    DESALINATION AND WATER TREATMENT, 2019, 158 : 225 - 232
  • [8] Investigation of chemical constituents from Spiraea prunifolia var. simpliciflora and their biological activities (vol 22, pg 255, 2017)
    Kim, Chung Sub
    Oh, Joonseok
    Suh, Won Se
    Jang, Sung Wan
    Subedi, Lalita
    Kim, Sun Yeou
    Choi, Sang Un
    Lee, Kang Ro
    PHYTOCHEMISTRY LETTERS, 2018, 25 : 27 - 27
  • [9] Prunioside A:: A new terpene glycoside from Spiraea prunifolia
    Oh, H
    Oh, GS
    Seo, WG
    Pae, HO
    Chai, KY
    Kwon, TO
    Lee, YH
    Chung, HT
    Lee, HS
    JOURNAL OF NATURAL PRODUCTS, 2001, 64 (07): : 942 - 944
  • [10] Enhancement of nitric oxide synthesis by the aqueous extract of Spiraea prunifolia var. simpliciflora's root in RAW 264.7 cells
    So, HS
    Park, R
    Oh, HM
    Chai, KY
    Lee, JH
    Chung, HT
    IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, 1999, 21 (02) : 343 - 355
12345