A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs

被引：17

作者：

Jang, Sung Wan ^{[1
]}

Suh, Won Se ^{[1
]}

Kim, Chung Sub ^{[1
]}

Kim, Ki Hyun ^{[1
]}

Lee, Kang Ro ^{[1
]}

机构：

[1] Sungkyunkwan Univ, Sch Pharm, Nat Prod Lab, Suwon 440746, South Korea

来源：

ARCHIVES OF PHARMACAL RESEARCH | 2015年 / 38卷 / 11期

基金：

新加坡国家研究基金会;

关键词：

Spiraea prunifolia var. simpliciflora; Phenolic glycoside; Cytotoxicity; LIGNAN GLYCOSIDE; PRUNIOSIDE-A; CONSTITUENTS; CAFFEOYL; DERIVATIVES; LEAVES;

D O I：

10.1007/s12272-015-0610-y

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The phytochemical investigation of the methanol extract from the twigs of Spiraea prunifolia var. simpliciflora (Rosaceae) using column chromatography led to the isolation of a new phenol glycoside, 1-O-(E)-caffeoyl-2-O-p-(E)-coumaroyl-beta-d-glucopyranose (1), together with 16 known phenolic compounds (2-17). The structure of this new compound was elucidated by analysis of spectroscopic data including 1D, 2D nuclear magnetic resonance and HR-FAB-MS data. The isolated compounds were tested for cytotoxicity against four human tumor cell lines in vitro using the sulforhodamine B bioassay.

引用

页码：1943 / 1951

页数：9

共 24 条

[1] CONSTITUENTS OF WEST-AFRICAN MEDICINAL-PLANTS .12. LIGNANS AND OTHER CONSTITUENTS FROM CARISSA-EDULIS [J].

ACHENBACH, H ;

WAIBEL, R ;

ADDAEMENSAH, I .

PHYTOCHEMISTRY, 1983, 22 (03) :749-753

[2] The chemical constituents of fresh Gentian root [J].

Ando, Hidehiro ;

Hirai, Yasuaki ;

Fujii, Mikio ;

Hori, Yumiko ;

Fukumura, Motonori ;

Niiho, Yujiro ;

Nakajima, Yoshijiro ;

Shibata, Toshiro ;

Toriizuka, Kazuo ;

Ida, Yoshiteru .

JOURNAL OF NATURAL MEDICINES, 2007, 61 (03) :269-279

[3] A New Triterpene Saponin from the Tubers of Stachys sieboldii [J].

Cho, Hyeon Kyung ;

Kim, Chung Sub ;

Woo, Kyeong Wan ;

Lee, Kang Ro .

BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2014, 35 (05) :1553-1555

[4]

FANG JM, 1992, PHYTOCHEMISTRY, V31, P3659, DOI 10.1016/0031-9422(92)83753-L

[5]

FONSECA S F, 1978, Phytochemistry (Oxford), V17, P499, DOI 10.1016/S0031-9422(00)89347-4

[6] Caffeoyl, coumaroyl, galloyl, and hexahydroxydiphenoyl glucoses from Balanophora japonica [J].

Jiang, ZH ;

Hirose, Y ;

Iwata, H ;

Sakamoto, S ;

Tanaka, T ;

Kouno, I .

CHEMICAL & PHARMACEUTICAL BULLETIN, 2001, 49 (07) :887-892

[7]

Jun CS, 2007, B KOREAN CHEM SOC, V28, P73

[8] A new flavonol glycoside from the aerial part of Rudbeckia laciniata [J].

Lee, Seung Young ;

Shin, Young June ;

Choi, Sang Un ;

Lee, Kang Ro .

ARCHIVES OF PHARMACAL RESEARCH, 2014, 37 (07) :834-838

[9]

Lee T.B., 2003, Coloured Flora of Korea

[10] A novel atisane diterpenoid from Spiraea japonica var. acuta [J].

Liu, Hai-Yang ;

Gao, Suo ;

Di, Ying-Tong ;

Chen, Chang-Xiang ;

Lue, Yang ;

Zhang, Li ;

Zheng, Qi-Tai ;

Hao, Xiao-Jiang .

HELVETICA CHIMICA ACTA, 2007, 90 (07) :1386-1390

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