HtrA - A renaissance protein

被引：5

作者：

Day, CL

Hinds, MG

机构：

[1] Univ Otago, Dept Biochem, Dunedin, New Zealand

[2] PO Royal Melbourne Hosp, Walter & Eliza Hall Inst Med Res, Parkville, Vic 3050, Australia

来源：

STRUCTURE | 2002年 / 10卷 / 06期

关键词：

D O I：

10.1016/S0969-2126(02)00782-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Initially identified as proteases, members of the HtrA/DegP family of proteins have also been shown to act as chaperones in bacteria, and more recently implicated, as regulators of apoptosis in mammals. Two new structures of mammalian HtrA2 and E. coli DegP provide insights into the origin of this plurality of function.

引用

页码：737 / 739

页数：3

共 11 条

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