Attention-deficit/hyperactivity disorder and impairment in executive functions: a barrier to weight loss in individuals with obesity?

被引:53
作者
Cortese, Samuele [1 ,2 ,7 ]
Comencini, Erika [1 ]
Vincenzi, Brenda [3 ]
Speranza, Mario [4 ,5 ]
Angriman, Marco [6 ]
机构
[1] Univ Verona, Child Neuropsychiat Unit, GB Rossi Hosp, Dept Life Sci & Reprod, I-37100 Verona, Italy
[2] NYU Langone Med Ctr, Phyllis Green & Randolph Cowen Inst Pediat Neuros, Ctr Child Study, New York, NY USA
[3] Massachusetts Gen Hosp, Schizophrenia Clin & Res Program, Boston, MA 02114 USA
[4] Univ Versailles St Quentin En Yvelines, EA4047, Versailles, France
[5] Versailles Gen Hosp, Le Chesnay, France
[6] Cent Hosp Bolzano, Child Neurol & Neurorehabil Unit, Dept Pediat, Bolzano, Italy
[7] Osped GB Rossi, Unita Autonoma Neuropsichiatria Infantile, I-37134 Verona, Italy
关键词
ADHD; Executive functions; Obesity; Treatment resistance; DEFICIT HYPERACTIVITY DISORDER; CHILDREN; ADHD; ASSOCIATION; PREVALENCE; ADULTS; METAANALYSIS; COMORBIDITY; CHILDHOOD; SYMPTOMS;
D O I
10.1186/1471-244X-13-286
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background: An increasing body of research points to a significant association of obesity to Attention-Deficit/ Hyperactivity Disorder (ADHD) and deficits in executive functions. There is also preliminary evidence suggesting that children with ADHD may be at risk of obesity in adulthood. Discussion: In this article, we discuss the evidence showing that ADHD and/or deficits in executive functions are a barrier to a successful weight control in individuals enrolled in weight loss programs. Impairing symptoms of ADHD or deficits in executive functions may foster dysregulated eating behaviors, such as binge eating, emotionally-induced eating or eating in the absence of hunger, which, in turn, may contribute to unsuccessful weight loss. ADHD-related behaviors or neurocognitive impairment may also hamper a regular and structured physical activity. There is initial research showing that treatment of comorbid ADHD and executive functions training significantly improve the outcome of obesity in individuals with comorbid ADHD or impairment in executive functions. Summary: Preliminary evidence suggests that comorbid ADHD and deficits in executive functions are a barrier to a successful weight loss in individuals involved in obesity treatment programs. If further methodologically sound evidence confirms this relationship, screening and effectively managing comorbid ADHD and/or executive functions deficits in individuals with obesity might have the potential to reduce not only the burden of ADHD but also the obesity epidemics.
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页数:7
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