Computational nanomedicine: modeling of nanoparticle-mediated hyperthermal cancer therapy

被引：0
作者：
Kaddi, Chanchala D. [1 ]
Phan, John H. [1 ]
Wang, May D. [2 ,3 ]
机构：
[1] Georgia Inst Technol, Wallace H Coulter Dept Biomed Engn, Atlanta, GA 30332 USA
[2] Georgia Inst Technol, Biomed Engn Dept, Winship Canc Inst, Parker H Petit Inst Bioengn & Biosci, Atlanta, GA 30332 USA
[3] Emory Univ, Atlanta, GA 30332 USA
来源：
NANOMEDICINE | 2013年 / 8卷 / 08期
基金：
美国国家科学基金会;
关键词：
bioinformatics; drug delivery; hyperthermia; mathematical modeling; nanomedicine; nanoparticle; pharmacokinetics; simulation; MAGNETIC NANOPARTICLES; PROSTATE-CANCER; GOLD-NANOPARTICLE; DRUG-DELIVERY; TUMOR; THERMOTHERAPY; FEASIBILITY; CHALLENGES; DYNAMICS; KINETICS;
D O I：
10.2217/NNM.13.117
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Nanoparticle-mediated hyperthermia for cancer therapy is a growing area of cancer nanomedicine because of the potential for localized and targeted destruction of cancer cells. Localized hyperthermal effects are dependent on many factors, including nanoparticle size and shape, excitation wavelength and power, and tissue properties. Computational modeling is an important tool for investigating and optimizing these parameters. In this review, we focus on computational modeling of magnetic and gold nanoparticle-mediated hyperthermia, followed by a discussion of new opportunities and challenges.
引用
收藏
页码：1323 / 1333
页数：11
相关论文
共 50 条
  • [31] Magnetic Nanoparticle-Mediated Heating for Biomedical Applications
    Kwizera, Elyahb Allie
    Stewart, Samantha
    Mahmud, Md Musavvir
    He, Xiaoming
    JOURNAL OF HEAT TRANSFER-TRANSACTIONS OF THE ASME, 2022, 144 (03):
  • [32] NANOPARTICLE-MEDIATED TREATMENT OF PULMONARY ARTERIAL HYPERTENSION
    Mosgoeller, W.
    Prassl, R.
    Zimmer, A.
    NANOMEDICINE: CANCER, DIABETES, AND CARDIOVASCULAR, CENTRAL NERVOUS SYSTEM, PULMONARY AND INFLAMMATORY DISEASES, 2012, 508 : 325 - 354
  • [33] A comparative study of sericin and gluten for magnetic nanoparticle-mediated drug delivery to breast cancer cell lines
    Jalilian, Saba
    Bahremand, Kiana
    Arkan, Elham
    Jaymand, Mehdi
    Aghaz, Faranak
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [34] Chitosan Nanoparticle-Mediated Delivery of Curcumin Suppresses Tumor Growth in Breast Cancer
    Mishra, Barnalee
    Yadav, Amit Singh
    Malhotra, Diksha
    Mitra, Tandrima
    Sinsinwar, Simran
    Radharani, N. N. V.
    Sahoo, Saroj Ranjan
    Patnaik, Srinivas
    Kundu, Gopal C.
    NANOMATERIALS, 2024, 14 (15)
  • [35] Nanoparticle-mediated targeted drug delivery for breast cancer treatment
    Liyanage, Piumi Y.
    Hettiarachchi, Sajini D.
    Zhou, Yiqun
    Ouhtit, Allal
    Seven, Elif S.
    Oztan, Cagri Y.
    Celik, Emrah
    Leblanc, Roger M.
    BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2019, 1871 (02): : 419 - 433
  • [36] Real-time, noninvasive optoacoustic monitoring of nanoparticle-mediated photothermal therapy of tumors
    Esenaliev, R. O.
    Petrov, Y. Y.
    Cicenaite, I.
    Chumakova, O. V.
    Petrova, I. Y.
    Patrikeev, I.
    Liopo, A.
    PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2007, 2007, 6437
  • [37] Mechanisms of Nanoparticle-Mediated siRNA Transfection by Melittin-Derived Peptides
    Hou, Kirk K.
    Pan, Hua
    Ratner, Lee
    Schlesinger, Paul H.
    Wickline, Samuel A.
    ACS NANO, 2013, 7 (10) : 8605 - 8615
  • [38] Recent Advances in Nanoparticle-Mediated Diagnosis and the Treatment of Pancreatic Cancer
    Nedelcu, Andreea
    Mocan, Teodora
    Grapa, Cristiana
    Mocan, Lucian
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (15)
  • [39] Nanoparticle-Mediated Hyperthermia and Cytotoxicity Mechanisms in Cancer
    Bala, Vanessa-Meletia
    Lampropoulou, Dimitra Ioanna
    Grammatikaki, Stamatiki
    Kouloulias, Vassilios
    Lagopati, Nefeli
    Aravantinos, Gerasimos
    Gazouli, Maria
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (01)
  • [40] Nanoparticle-Mediated STING Agonist Delivery for Enhanced Cancer Immunotherapy
    Zhou, Qinghao
    Zhou, Yu
    Li, Taiyuan
    Ge, Zhishen
    MACROMOLECULAR BIOSCIENCE, 2021, 21 (08)
12345