Comparative inhibitory properties of some Indian medicinal plant extracts against photosensitization-induced lipid damage

被引:18
作者
Bhattacharya, Sayanti [2 ]
Kaniat, Jaya P. [3 ]
Bandyopadhyay, Sandip K. [2 ]
Chattopadhyay, Subrata [1 ,3 ]
机构
[1] Bhabha Atom Res Ctr, Div Bioorgan, Bombay 400085, Maharashtra, India
[2] Dr BC Roy Postgrad Inst Basic Med Sci, Dept Biochem, Kolkata 700020, India
[3] Bhabha Atom Res Ctr, Radiat Biol & Hlth Sci Div, Bombay 400085, Maharashtra, India
关键词
Photosensitization; Lipids; Protection; Plant extracts; SINGLET OXYGEN; CELL-GROWTH; EMBLICA-OFFICINALIS; PHYLLANTHUS-EMBLICA; OXIDATIVE STRESS; LINES;
D O I
10.1016/j.foodchem.2008.08.047
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The protective activities of Emblica of officinalis, Terminalia bellerica and Terminalia chebula ethanol extracts against photosensitization-induced oxidation of rat liver mitochondrial lipid were assessed. All the extracts Could effectively prevent lipid peroxidation, as assessed by measuring thiobarbituric acid-reactive Substrates, lipid hydroperoxide, conjugated diene and 4-hydroxynonenal. The E. officinalis extract was the most potent, revealing its superior ability to scavenge O-1(2). The extracts also afforded excellent protection against iron-mediated lipid peroxidation that might also be useful in reducing photo-induced iron toxicity. The activities of the extracts were primarily due to their constituent phenolics. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:975 / 979
页数:5
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