The first latent green fluorophores for the detection of azoreductase activity in bacterial cultures

被引：54

作者：

Chevalier, Arnaud ^{[1
]}

Mercier, Claire ^{[2
]}

Saurel, Laura ^{[2
]}

Orenga, Sylvain ^{[2
]}

Renard, Pierre-Yves ^{[1
]}

Romieu, Anthony ^{[1
]}

机构：

[1] Univ Rouen, INSA Rouen, COBRA, UMR 6014 & FR 3038, F-76821 Mont St Aignan, France

[2] BioMerieux, R&D Microbiol, F-38390 La Balme Les Grottes, France

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 78期

关键词：

FLUORESCENCE PROBE; FAR-RED; NITROREDUCTASE; LUMINESCENT; DYES;

D O I：

10.1039/c3cc44798g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient synthesis of original bio-reductive probes suitable for the detection of azoreductases from the fluorescent rhodamine 110 dye is presented. A "turn-on'' green fluorescence response upon reduction of the two diazo bonds of these latent fluorophores was observed both in vitro and in the context of bacterial cultures.

引用

页码：8815 / 8817

页数：3

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