Reactions of regioisomeric 3,3-dimethyl- and 2,2-dimethyl-6-trifluoromethyl-2,3-dihydro-4-pyrones with N-nucleophiles

被引：6
|
作者：
Sosnovskikh, VY [1 ]
Mel'nikov, MY [1 ]
机构：
[1] AM Gorky Ural State Univ, Ekaterinburg 620083, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 1999年 / 48卷 / 05期
基金：
俄罗斯基础研究基金会;
关键词：
substituted 2,3-dihydro-4-pyrones; substituted tetrahydro-4-pyrones; CF3-containing aminoenones; pyrazoles; Delta(2)-isoxazolines;
D O I：
10.1007/BF02494648
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Reactions of 2,2-dimethyl-6-trifluoromethyl-2,3-dihydro-4-pyrone with ethylenediamine, hydrazine, or hydroxylamine yield 5-methyl-7-trifluoromethyl-2,3-dihydro-1H-1,4-diazepine, 3(5)-(2-hydroxy-2-methylpropyl)-5(3)-trifluoromethylpyrazole, and 5-hydroxy-3-(2-hydroxy-2-methylpropyl)-5-trifluoromtthyl-Delta(2)-isoxazoline, respectively. The same compounds were obtained from 2-amino-1,1,1-trifluoro-6-hydroxy-6-methylhept-2(Z)-en-4-one and 2-hydroxy-6,6-dimethyl-2-trifluoromethyltetrahydro-4-pyrone.
引用
收藏
页码：975 / 978
页数：4
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