Reactions of regioisomeric 3,3-dimethyl- and 2,2-dimethyl-6-trifluoromethyl-2,3-dihydro-4-pyrones with N-nucleophiles

被引：6

作者：

Sosnovskikh, VY ^{[1
]}

Mel'nikov, MY ^{[1
]}

机构：

[1] AM Gorky Ural State Univ, Ekaterinburg 620083, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 1999年 / 48卷 / 05期

基金：

俄罗斯基础研究基金会;

关键词：

substituted 2,3-dihydro-4-pyrones; substituted tetrahydro-4-pyrones; CF3-containing aminoenones; pyrazoles; Delta(2)-isoxazolines;

D O I：

10.1007/BF02494648

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reactions of 2,2-dimethyl-6-trifluoromethyl-2,3-dihydro-4-pyrone with ethylenediamine, hydrazine, or hydroxylamine yield 5-methyl-7-trifluoromethyl-2,3-dihydro-1H-1,4-diazepine, 3(5)-(2-hydroxy-2-methylpropyl)-5(3)-trifluoromethylpyrazole, and 5-hydroxy-3-(2-hydroxy-2-methylpropyl)-5-trifluoromtthyl-Delta(2)-isoxazoline, respectively. The same compounds were obtained from 2-amino-1,1,1-trifluoro-6-hydroxy-6-methylhept-2(Z)-en-4-one and 2-hydroxy-6,6-dimethyl-2-trifluoromethyltetrahydro-4-pyrone.

引用

页码：975 / 978

页数：4

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