Factors associated with health-related quality of life in renal transplant recipients: results of a national survey in France

被引:59
作者
Gentile, Stephanie [1 ,2 ]
Beauger, Davy [1 ]
Speyer, Elodie [5 ,6 ]
Jouve, Elisabeth [2 ]
Dussol, Bertrand [3 ]
Jacquelinet, Christian [4 ]
Briancon, Serge [5 ,6 ]
机构
[1] Univ Aix Marseille, Fac Med, Lab Sante Publ, EA 3279, Marseille, France
[2] CHU Marseille, Serv Sante Publ & Informat Med, Marseille, France
[3] CHU Marseille, Ctr Nephrol & Transplantat Renale, Marseille, France
[4] Agence Biomed, Paris, France
[5] CHU Nancy, Nancy, France
[6] Univ Paris 05, Univ Lorraine, EA 4360, Nancy, France
关键词
Associated factors; Cross-sectional multicenter study; Quality of life; Renal transplant recipient; ReTransQol; SF-36; KIDNEY-TRANSPLANTATION; DIALYSIS; DISEASE; ANXIETY; HEMODIALYSIS; EPIDEMIOLOGY; MEDICATION; DEPRESSION; DISORDERS; IMPACT;
D O I
10.1186/1477-7525-11-88
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Background: This study aims to identify factors associated with health related quality of life (HRQOL) through a comprehensive analysis of sociodemographic and clinical variables among a representative sample size of renal transplant recipients (RTR) in France. Methods: A cross-sectional multicenter study was carried out in 2008. All RTR over 18 years old with a functioning graft for at least one year were included. Data included socio-demographic, health status, and treatment characteristics. To evaluate HRQOL, the Short Form-36 Health Survey (SF-36) and a HRQOL instrument for RTR (ReTransQol) were administered. Multivariate linear regression models were performed. Results: A total of 1061 RTR were included, with a return rate of 72.5%. The variance explained in regression models of SF-36 ranges from 20% to 40% and from 9% to 33% for ReTransQol. The variables which decreased scores of both HRQOL questionnaires were: females, unemployment, lower education, living alone, high BMI, diabetes, recent critical illness and hospitalization, non-compliance, a long duration of dialysis and treatment side effects. Specific variables which decreased ReTransQol scores were dismissal and a recent surgery on the graft. These which decreased SF36 scores were being old and a recent infectious disease. The variables the most predictors of worse HRQOL were: side effects, infectious disease, recent hospitalization and female gender. Conclusions: The originality of our study's findings was that novel variables, particularly treatment side effects and unemployment, have a negative effect on quality of life of RTR. The French Biomedicine Agency and the National Health Institute for Public Health Surveillance conduct specific actions for professional reintegration and therapeutic education programs in the national plan to improve the HRQOL of people living with chronic diseases.
引用
收藏
页数:12
相关论文
共 50 条
[41]   Impact of personality and psychological distress on health-related quality of life in kidney transplant recipients [J].
Prihodova, Lucia ;
Nagyova, Iveta ;
Rosenberger, Jaroslav ;
Roland, Robert ;
van Dijk, Jitse P. ;
Groothoff, Johan W. .
TRANSPLANT INTERNATIONAL, 2010, 23 (05) :484-492
[42]   Factors associated to depression in renal transplant recipients in Panama [J].
Vasquez, Vivian ;
Novarro, Nelson ;
Valdes, Regulo A. ;
Britton, Gabrielle B. .
INDIAN JOURNAL OF PSYCHIATRY, 2013, 55 (03) :273-278
[43]   Health-related quality of life in metabolic syndrome: The Korea National Health and Nutrition Examination Survey 2005 [J].
Park, Sang Shin ;
Yoon, Yeong Sook ;
Oh, Sang Woo .
DIABETES RESEARCH AND CLINICAL PRACTICE, 2011, 91 (03) :381-388
[44]   Health-related quality of life in kidney transplant patients with diabetes [J].
Dukes, Jonathan L. ;
Seelam, Susmitha ;
Lentine, Krista L. ;
Schnitzler, Mark A. ;
Neri, Luca .
CLINICAL TRANSPLANTATION, 2013, 27 (05) :E554-E562
[45]   Factors associated with adolescents? health-related quality of life [J].
Alencar, Nadyelle Elias Santos ;
da Silva, Grazielle Roberta Freitas ;
Gouveia, Marcia Teles de Oliveira ;
da Silva, Ana Roberta Vilarouca .
ACTA PAULISTA DE ENFERMAGEM, 2022, 35 :1-9
[46]   Patient and Parent Psychosocial Factors Associated With Health-related Quality of Life in Pediatric Inflammatory Bowel Disease [J].
Herzer, Michele ;
Denson, Lee A. ;
Baldassano, Robert N. ;
Hommel, Kevin A. .
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2011, 52 (03) :295-299
[47]   Kidney Transplantation Improves Health-Related Quality of Life in Older Recipients [J].
de Boer, Silke E. ;
Knobbe, Tim. J. ;
Kremer, Daan ;
van Munster, Barbara C. ;
Nieuwenhuijs-Moeke, Gertrude J. ;
Pol, Robert A. ;
Bakker, Stephan J. L. ;
Berger, Stefan P. ;
Sanders, Jan Stephan F. .
TRANSPLANT INTERNATIONAL, 2024, 37
[48]   Factors predicting health-related quality of life in pediatric liver transplant recipients in the functional outcomes group [J].
Alonso, Estella M. ;
Martz, Karen ;
Wang, Deli ;
Yi, Michael S. ;
Neighbors, Katie ;
Varni, James W. ;
Bucuvalas, John C. .
PEDIATRIC TRANSPLANTATION, 2013, 17 (07) :605-611
[49]   Investigation of measurement invariance in longitudinal health-related quality of life in preemptive or previously dialyzed kidney transplant recipients [J].
Auneau-Enjalbert, Line ;
Blanchin, Myriam ;
Giral, Magali ;
Meurette, Aurelie ;
Morelon, Emmanuel ;
Albano, Laetitia ;
Hardouin, Jean-Benoit ;
Sebille, Veronique .
QUALITY OF LIFE RESEARCH, 2022, 31 (02) :607-620
[50]   Psychological Factors Are Associated with Changes in the Health-related Quality of Life in Inflammatory Bowel Disease [J].
Iglesias-Rey, Marta ;
Barreiro-de Acosta, Manuel ;
Caamano-Isorna, Francisco ;
Rodriguez, Isabel V. ;
Ferreiro, Rocio ;
Lindkvist, Bjoern ;
Gonzalez, Aurelio L. ;
Dominguez-Munoz, J. E. .
INFLAMMATORY BOWEL DISEASES, 2014, 20 (01) :92-102