Myocardial recovery with mechanical circulatory support

被引：17

作者：

Chaggar, Parminder S. ^{[1
,2
]}

Williams, Simon G. ^{[1
]}

Yonan, Nizar ^{[1
]}

Fildes, James ^{[1
,2
]}

Venkateswaran, Rajamiyer ^{[1
]}

Shaw, Steven M. ^{[1
]}

机构：

[1] Univ Hosp South Manchester, Transplant Unit, Southmoor Rd, Manchester M23 9LT, Lancs, England

[2] Univ Manchester, Manchester Collaborat Ctr Inflammat Res, Manchester, Lancs, England

来源：

EUROPEAN JOURNAL OF HEART FAILURE | 2016年 / 18卷 / 10期

关键词：

Heart failure; Myocardial recovery; Mechanical circulatory support; Left ventricular assist device; VENTRICULAR-ASSIST DEVICE; FAILING HUMAN HEART; IDIOPATHIC DILATED CARDIOMYOPATHY; CARDIAC RECOVERY; GENE-EXPRESSION; PHARMACOLOGICAL THERAPY; CYTOSKELETAL PROTEINS; CELLULAR HYPERTROPHY; DYNAMIC REGULATION; CLINICAL RECOVERY;

D O I：

10.1002/ejhf.575

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Mechanical circulatory support (MCS) is instituted in patients with advanced heart failure, some of who may experience sufficient recovery in cardiac function to allow withdrawal of mechanical support. The incidence of left ventricular recovery with MCS is unclear as reported series in the literature demonstrate widely divergent rates. A number of clinical parameters (including echocardiographic, haemodynamic and physiological) are used to indicate likely left ventricular recovery during pump speed reduction but no internationally agreed definition exists. Withdrawal of MCS is not without risk and so robust clinical and biochemical definitions are important to minimize patient morbidity and mortality. Here we review our current understanding of left ventricular recovery with MCS.

引用

页码：1220 / 1227

页数：8

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