Exhaled Breath Condensate An overview

被引:78
作者
Davis, Michael D. [1 ]
Montpetit, Alison [1 ]
Hunt, John [2 ]
机构
[1] Virginia Commonwealth Univ, Dept Adult Hlth & Nursing Syst, Sch Nursing, Richmond, VA 23298 USA
[2] Univ Virginia, Dept Pediat Pulmonol Allergy & Immunol, Charlottesville, VA 22908 USA
关键词
Exhaled breath condensate; Biomarker; Airway; Exhalate; NONINVASIVE EVALUATION; LUNG-DISEASE; ASTHMA; PH; CHILDREN; COLLECTION; CYTOKINES; DILUTION; MARKER; SALIVA;
D O I
10.1016/j.iac.2012.06.014
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Exhaled breath condensate (EBC) is a promising source of biomarkers of lung disease. EBC may be thought of either as a body fluid or as a condensate of exhaled gas. There are 3 principal contributors to EBC: variable-sized particles or droplets that are aerosolized from the airway lining fluid, distilled water that condenses from gas phase out of the nearly water-saturated exhalate, and water-soluble volatiles that are exhaled and absorbed into the condensing breath. The nonvolatile constituents and the water-soluble volatile constituents are of particular interest. Several key issues are discussed in this article.
引用
收藏
页码:363 / +
页数:14
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