Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii in South America

被引：44

作者：

Hernan Rodriguez, Carlos ^{[1
]}

Balderrama Yarhui, Norah ^{[1
]}

Nastro, Marcela ^{[1
]}

Nunez Quezada, Tamara ^{[2
]}

Castro Canarte, Glenda ^{[3
]}

Magne Ventura, Raquel ^{[4
]}

Ugarte Cuba, Tayita ^{[5
]}

Valenzuela, Natalia ^{[6
]}

Roach, Freddy ^{[6
]}

Ines Mota, Maria ^{[7
]}

Burger, Noelia ^{[7
]}

Aguayo, Gladys Velazquez ^{[8
]}

Ortellado-Canese, Juana ^{[8
]}

Bruni, Geni ^{[9
]}

Pandolfo, Cecilia ^{[9
]}

Bastyas, Nadya ^{[9
]}

Famiglietti, Angela ^{[1
]}

机构：

[1] Univ Buenos Aires, Fac Farm & Bioquim, Bacteriol Lab, Hosp Clin Jose de San Martin, Buenos Aires, DF, Argentina

[2] Hosp IESS Teodoro Maldonando Carbo, Guayaquil, Ecuador

[3] Hosp Infectol Jose Daniel Rodriguez Mariduena, Guayaquil, Ecuador

[4] Hosp Materno Iinfantil San Martin de Porres, Ibuelo, Cochabamba, Bolivia

[5] Hosp Nino Manuel Ascencio Villarroel, Cochabamba, Bolivia

[6] Hosp Dr Leonardo Guzman, Antofagasta, Chile

[7] Cooperat Asistencial Med Este Colonia, Rosario, Uruguay

[8] UMA, Hosp Clin FCM, Asuncion, Paraguay

[9] Hosp Nuestro Senora Del Carmen OSEP, Mendoza, Argentina

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 2016年 / 65卷

关键词：

MULTIPLEX PCR; DISSEMINATION; EMERGENCE; LINEAGES; CLONES; SPREAD; GENES;

D O I：

10.1099/jmm.0.000328

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

One hundred and twenty-six epidemiologically sequential, unrelated, carbapenem-resistant Acinetobacter baumannii isolates from nine hospitals in six countries of South America were collected between July 2013 and June 2014. Genes coding for Ambler class D and B carbapenemases were sought by PCR. All isolates were typed using the 3-locus sequence typing and bla(OXA-51-like) sequence-based typing techniques. The bla(OXA-23) gene was recovered in all the participating hospitals and in all the isolates of seven of nine medical centres. The bla(OXA-72) gene was only recovered in the two medical centres from Guayaquil city, Ecuador. Trilocus sequence typing revealed the presence of sequence groups SG2, SG4 and SG5. bla(OXA-51-like) sequence-based typing revealed the presence of bla(OXA-132), bla(OXA-65), bla(OXA-69) and bla(OXA-64). Our results showed that the population of carbapenem-resistant A. baumannii in South America was principally associated with ST79, ST25 and ST15 (92 %) and harboured the bla(OXA-23) gene mainly. CC2 was not detected.

引用

页码：1088 / 1091

页数：4

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