Structure-based design of agrochemicals

被引:110
作者
Walter, MW [1 ]
机构
[1] Eli Lilly & Co, Windlesham GU20 6PH, Surrey, England
关键词
D O I
10.1039/b100919m
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review covers recent advances in the structure-based design of agrochemicals. The three main sectors of agrochemistry, i.e. herbicides, insecticides, and fungicides are covered. The literature in this field to the present date is reviewed and 88 references are cited.
引用
收藏
页码:278 / 291
页数:14
相关论文
共 96 条
[1]   Automation of X-ray crystallography [J].
Abola, E ;
Kuhn, P ;
Earnest, T ;
Stevens, RC .
NATURE STRUCTURAL BIOLOGY, 2000, 7 (Suppl 11) :973-977
[2]   Structure-based drug design [J].
Amzel, LM .
CURRENT OPINION IN BIOTECHNOLOGY, 1998, 9 (04) :366-369
[3]   Crystal structure of the ternary complex of 1,3,8-trihydroxynaphthalene reductase from Magnaporthe grisea with NADPH and an active-site inhibitor [J].
Andersson, A ;
Jordan, D ;
Schneider, G ;
Lindqvist, Y .
STRUCTURE, 1996, 4 (10) :1161-1170
[4]   DESIGN OF ENZYME-INHIBITORS USING ITERATIVE PROTEIN CRYSTALLOGRAPHIC ANALYSIS [J].
APPELT, K ;
BACQUET, RJ ;
BARTLETT, CA ;
BOOTH, CLJ ;
FREER, ST ;
FUHRY, MAM ;
GEHRING, MR ;
HERRMANN, SM ;
HOWLAND, EF ;
JANSON, CA ;
JONES, TR ;
KAN, CC ;
KATHARDEKAR, V ;
LEWIS, KK ;
MARZONI, GP ;
MATTHEWS, DA ;
MOHR, C ;
MOOMAW, EW ;
MORSE, CA ;
OATLEY, SJ ;
OGDEN, RC ;
REDDY, MR ;
REICH, SH ;
SCHOETTLIN, WS ;
SMITH, WW ;
VARNEY, MD ;
VILLAFRANCA, JE ;
WARD, RW ;
WEBBER, S ;
WEBBER, SE ;
WELSH, KM ;
WHITE, J .
JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (07) :1925-1934
[5]   The biosynthesis and metabolism of the aspartate derived amino acids in higher plants [J].
Azevedo, RA ;
Arruda, P ;
Turner, WL ;
Lea, PJ .
PHYTOCHEMISTRY, 1997, 46 (03) :395-419
[6]   Design of scytalone dehydratase inhibitors as rice blast fungicides: Derivatives of norephedrine [J].
Basarab, GS ;
Jordan, DB ;
Gehret, TC ;
Schwartz, RS ;
Wawrzak, Z .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (11) :1613-1618
[7]   The Protein Data Bank [J].
Berman, HM ;
Westbrook, J ;
Feng, Z ;
Gilliland, G ;
Bhat, TN ;
Weissig, H ;
Shindyalov, IN ;
Bourne, PE .
NUCLEIC ACIDS RESEARCH, 2000, 28 (01) :235-242
[8]   Structure and function of cytochrome bc complexes [J].
Berry, EA ;
Guergova-Kuras, M ;
Huang, LS ;
Crofts, AR .
ANNUAL REVIEW OF BIOCHEMISTRY, 2000, 69 :1005-1075
[9]   The crystal structure of plant acetohydroxy acid isomeroreductase complexed with NADPH, two magnesium ions and a herbicidal transition state analog determined at 1.65 angstrom resolution [J].
Biou, V ;
Dumas, R ;
CohenAddad, C ;
Douce, R ;
Job, D ;
PebayPeyroula, E .
EMBO JOURNAL, 1997, 16 (12) :3405-3415
[10]   Structure-based library design:: molecular modelling merges with combinatorial chemistry [J].
Böhm, HJ ;
Stahl, M .
CURRENT OPINION IN CHEMICAL BIOLOGY, 2000, 4 (03) :283-286