High performance cholesterol sensor based on ZnO nanotubes grown on Si/Ag electrodes

被引：76

作者：

Ahmad, Rafiq ^{[1
]}

Tripathy, Nirmalya ^{[1
]}

Kim, Sang Hoon ^{[2
]}

Umar, Ahmad ^{[2
]}

Al-Hajry, A. ^{[2
]}

Hahn, Yoon-Bong ^{[1
]}

机构：

[1] Chonbuk Natl Univ, Sch Semicond & Chem Engn, Dept BIN Fus Technol, Jeonju 561756, South Korea

[2] Najran Univ, Promising Ctr Sensors & Elect Devices PCSED, Najran 11001, Saudi Arabia

来源：

ELECTROCHEMISTRY COMMUNICATIONS | 2014年 / 38卷

基金：

新加坡国家研究基金会;

关键词：

ZnO nanotubes; Cholesterol biosensor; Wide linear range; High sensitivity; HYDROGEN-PEROXIDE BIOSENSOR; OXIDE NANOSTRUCTURES; HORSERADISH-PEROXIDASE; GLUCOSE BIOSENSORS; ARRAY; IMMOBILIZATION; NANORODS;

D O I：

10.1016/j.elecom.2013.10.028

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

Zinc oxide nanotube (ZNT) arrays were grown on Si/Ag substrate by one-step chemical process in an aqueous solution and further used as a working electrode to fabricate an enzyme-based cholesterol biosensor through immobilization of cholesterol oxidase (ChOx). The fabricated biosensors exhibit high and reproducible sensitivity of 79.40 mu A/mM/cm(2), wide linear range from 1.0 mu M to 13.0 mM, fast response time of similar to 2 s and ultra-low detection limit of 0.5 nM (S/N = 3) for cholesterol sensing. The anti-interference ability and long-term stability of the biosensor were also assessed. Finally, the biosensor was applied to analyze cholesterol concentration in human serum samples. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：4 / 7

页数：4

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