Principles of Nuclear Medicine Imaging: Planar, SPECT, PET, Multi-modality, and Autoradiography Systems

被引：62
作者：
Zanzonico, Pat [1 ,2 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, Dept Med Phys, New York, NY 10021 USA
[2] Mem Sloan Kettering Canc Ctr, Dept Radiol, New York, NY 10021 USA
来源：
RADIATION RESEARCH | 2012年 / 177卷 / 04期
关键词：
OF-FLIGHT PET; INSTRUMENTATION; TOMOGRAPHY; SCANNERS; FUSION;
D O I：
10.1667/RR2577.1
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The underlying principles of nuclear medicine imaging involve the use of unsealed sources of radioactivity in the form of radiopharmaceuticals. The ionizing radiations that accompany the decay of the administered radioactivity can be quantitatively detected, measured, and imaged in vivo with instruments such as gamma cameras. This paper reviews the design and operating principles, as well as the capabilities and limitations, of instruments used clinically and preclinically for in vivo radionuclide imaging. These include gamma cameras, single-photon emission computed tomography (SPECT) scanners, and positron emission tomography (PET) scanners. The technical basis of autoradiography is reviewed as well. (C) 2012 by Radiation Research Society
引用
收藏
页码：349 / 364
页数：16
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