CRISPR-based RNA editing: diagnostic applications and therapeutic options

被引:10
作者
Gulei, Diana [1 ]
Raduly, Lajos [2 ,3 ]
Berindan-Neagoe, Ioana [1 ,2 ,4 ]
Calin, George Adrian [5 ,6 ]
机构
[1] Univ Med & Pharm Iuliu Hatieganu, MedFuture Res Ctr Adv Med, Cluj Napoca, Romania
[2] Univ Med & Pharm Iuliu Hatieganu, Res Ctr Funct Genom Biomed & Translat Med, Cluj Napoca, Romania
[3] Univ Agr Sci & Vet Med, Dept Pathophysiol, Cluj Napoca, Romania
[4] Oncol Inst Prof Dr Ion Chiricuta, Dept Funct Genom & Expt Pathol, Cluj Napoca, Romania
[5] Univ Texas MD Anderson Canc Ctr, Dept Expt Therapeut, 1515 Holcombe Blvd,Unit 1950, Houston, TX 77030 USA
[6] Univ Texas MD Anderson Canc Ctr, Ctr RNA Inference & Noncoding RNAs, Houston, TX 77030 USA
基金
美国国家卫生研究院;
关键词
DNA/RNA editing; diagnostic; non-coding RNA; programmable nucleases; therapy; GENE-THERAPY; NONCODING RNAS; MUTATIONS; MICRORNAS; EFFICIENT; TARGETS; GUIDE;
D O I
10.1080/14737159.2019.1568242
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
引用
收藏
页码:83 / 88
页数:6
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