Exploring an Anti-Crystal Engineering Approach to the Preparation of Pharmaceutically Active Ionic Liquids

被引:110
作者
Dean, Pamela M. [1 ]
Turanjanin, Jelena [1 ]
Yoshizawa-Fujita, Masahiro [1 ]
MacFarlane, Douglas R. [1 ]
Scott, Janet L. [1 ]
机构
[1] Monash Univ, Sch Chem, Clayton, Vic 3800, Australia
关键词
INTERMOLECULAR INTERACTIONS; SUPRAMOLECULAR SYNTHONS; ACESULFAMATE; PHASES;
D O I
10.1021/cg8009496
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of salts, some of which are ionic liquids, are prepared from cations and anions drawn from Active Pharmaceutical Ingredients (APIs) and Generally Recognized As Safe (GRAS) materials. Using the solid-state structures of the crystalline salts as a basis, an anti-crystal engineering approach to the preparation of "Active Ionic Liquids" (AILs) is explored.
引用
收藏
页码:1137 / 1145
页数:9
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