Dynamics of telomere length in captive Siamese cobra (Naja kaouthia) related to age and sex

被引：10

作者：

Singchat, Worapong ^{[1
]}

Kraichak, Ekaphan ^{[2
]}

Tawichasri, Panupong ^{[1
]}

Tawan, Tanapong ^{[3
]}

Suntronpong, Aorarat ^{[1
]}

Sillapaprayoon, Siwapech ^{[1
]}

Phatcharakullawarawat, Rattanin ^{[4
]}

Muangmai, Narongrit ^{[5
]}

Suntrarachun, Sunutcha ^{[3
]}

Baicharoen, Sudarath ^{[6
]}

Punyapornwithaya, Veerasak ^{[7
]}

Peyachoknagul, Surin ^{[1
]}

Chanhome, Lawan ^{[3
]}

Srikulnath, Kornsorn ^{[1
,8
,9
,10
]}

机构：

[1] Kasetsart Univ, Fac Sci, Dept Genet, Lab Anim Cytogenet & Comparat Genom ACCG, Bangkok 10900, Thailand

[2] Kasetsart Univ, Fac Sci, Dept Bot, Bangkok, Thailand

[3] Thai Red Cross Soc, QSMI, Bangkok, Thailand

[4] Mildpets Anim Hosp, Bangkok, Thailand

[5] Kasetsart Univ, Fac Fisheries, Dept Fishery Biol, Bangkok, Thailand

[6] Zool Pk Org Royal Patronage His Majesty King ZPO, Bur Conservat & Res, Bangkok, Thailand

[7] Chiang Mai Univ, Fac Vet Med, Chiang Mai, Thailand

[8] KU, Ctr Adv Studies Trop Nat Resources, NRU, CASTNAR, Bangkok, Thailand

[9] Ctr Excellence Agr Biotechnol AG BIO PERDO CHE, Bangkok, Thailand

[10] Kasetsart Univ, Omics Ctr Agr Bioresources Food & Hlth, OmiKU, Bangkok, Thailand

来源：

ECOLOGY AND EVOLUTION | 2019年 / 9卷 / 11期

关键词：

age; hormone; sex; snake; telomere; QUANTITATIVE PCR; SNAKES; ASSAY; CHROMOSOMES; EVOLUTION;

D O I：

10.1002/ece3.5208

中图分类号：

Q14 [生态学（生物生态学）];

学科分类号：

071012 ; 0713 ;

摘要：

Telomeres comprise tandem repeated DNA sequences that protect the ends of chromosomes from deterioration or fusion with neighboring chromosomes, and their lengths might vary with sex and age. Here, age- and sex-related telomere lengths in male and female captive Siamese cobras (Naja kaouthia) were investigated using quantitative real-time polymerase chain reaction based on cross-sectional data. A negative correlation was shown between telomere length and body size in males but not in females. Age-related sex differences were also recorded. Juvenile female snakes have shorter telomeres relative to males at up to 5 years of age, while body size also rapidly increases during this period. This suggests that an accelerated increase in telomere length of female cobra results from sex hormone stimulation to telomerase activity, reflecting sexually dimorphic phenotypic traits. This might also result from amplification of telomeric repeats on sex chromosomes. By contrast, female Siamese cobras older than 5 years had longer telomeres than males. Diverse sex hormone levels and oxidative stress parameters between sexes may affect telomere length.

引用

页码：6366 / 6377

页数：12

共 46 条

[1]

[Anonymous], 2009, METHODS SOCIAL NEURO

[2] Evolutionary Dynamics of the W Chromosome in Caenophidian Snakes [J].