Enantioselective synthesis of cuparane sesquiterpenes. Synthesis of (-)-cuparene and (-)-delta-cuparenol

被引：31

作者：

Abad, A

Agullo, C

Arno, M

Cunat, AC

Garcia, MT

Zaragoza, RJ

机构：

[1] Depto. de Quim. Orgánica, Facultad de Químicas, Universidad de Valencia, E-46100 Burjassot, Valencia

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1996年 / 61卷 / 17期

关键词：

D O I：

10.1021/jo960463g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(-)-Cuparene land (-)-delta-cuparenol, two cuparane-type sesquiterpenoids, were synthesized from beta-cyclogeraniol in 47% and 27% overall yield, respectively, using a Katsuki-Sharpless asymmetric epoxidation, a pinacollic rearrangement, and a Robinson annulation as key synthetic steps.

引用

页码：5916 / 5919

页数：4

共 16 条

[1]

ABAD A, 1993, SYNLETT, P895

[2] SYNTHESIS OF (-)-BORJATRIOL [J].