Expeditious approach to the Amarylidaceae alkaloids, crinasiadine and its analogues, via a palladium-catalyzed intramolecular direct C-H arylation

被引：0
作者：
Mishra, Sourabh [1 ]
De, Subhadip [1 ]
Kakde, Badrinath N. [1 ]
Dey, Dhananjay [1 ]
Bisai, Alakesh [1 ]
机构：
[1] Indian Inst Sci Educ & Res IISER Bhopal, Dept Chem, Bhopal 462023, MP, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY | 2013年 / 52卷 / 8-9期
关键词：
Catalysis; Biaryl-coupling; Palladium; Alkaloids; Arylation; Crinasiadine; Phenanthridone; Phenanthridine; Dihydrophenanthridine; BIARYL COUPLING REACTION; BENZYNE CYCLIZATION; MEDIATED SYNTHESIS; PARP-1; INHIBITORS; ARYL CHLORIDES; DERIVATIVES; PHENANTHRIDINE; PD(OAC)(2); REAGENT; BU3P;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple and efficient approach to the core skeleton of various Amaryllidaceae alkaloids such as phenanthridones, phenanthridines and 5, 6-dihydrophenanthridines has been achieved. The methodology involves a palladium catalyzed direct biaryl-coupling of 2-halobenzoylamines/2-halobenzylamine derivatives.
引用
收藏
页码：1093 / 1102
页数：10
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