Tandem Gold-Catalyzed HydrosilyloxylationAldol and Mannich Reaction with Alkynylaryloxysilanols in 6-exo Mode

被引：13

作者：

Lee, Euichul ^{[1
]}

Ryu, Taekyu ^{[1
]}

Park, Youngchul ^{[1
]}

Park, Sangjune ^{[1
]}

Lee, Phil Ho ^{[1
]}

机构：

[1] Kangwon Natl Univ, Dept Chem, Chunchon 200701, South Korea

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2013年 / 355卷 / 08期

基金：

新加坡国家研究基金会;

关键词：

aldol reaction; 6-exo mode; gold; hydrosilyloxylation; Mannich reaction; CONTAINING AZOMETHINE YLIDES; TERMINAL ALKYNES; ALPHA; BETA-UNSATURATED KETONES; INTRAMOLECULAR CYCLIZATION; REGIOSELECTIVE SYNTHESIS; EFFICIENT SYNTHESIS; ADDITION-REACTION; ASYMMETRIC ALDOL; ALLYLIC ALCOHOLS; ISOMERIZATION;

D O I：

10.1002/adsc.201300244

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The tandem gold-catalyzed hydrosilyloxylationaldol and hydrosilyloxylationMannich reactions were developed through the formation of an enol silyl ether catalytically generated in situ from alkynylaryloxysilanols in the 6-exo mode in one reaction vessel.

引用

页码：1585 / 1596

页数：12

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