Ionian Sea (western Greece) is a plate-boundary region of high seismicity and complex tectonics, dominated by frequent earthquake activity along the right-lateral Cephalonia transform fault. We present an analysis of 30-s GPS data from five (5) continuous stations of NOANET (NOA permanent GPS network) spanning the period 2007-2010. Our results show N-S crustal shortening onshore Lefkada island of the order of 2-3 mm/yr which is probably related to increased locking on the offshore Lefkada fault. We also calculated a large difference (1:3) in the principal strain rate amplitude between extension and shortening for the central Ionian Sea. (C) 2012 Elsevier Ltd. All rights reserved.