The biology of influenza viruses

被引：768

作者：

Bouvier, Nicole M. ^{[1
,2
]}

Palese, Peter ^{[1
,2
]}

机构：

[1] Mt Sinai Sch Med, Dept Microbiol, New York, NY 10029 USA

[2] Mt Sinai Sch Med, Dept Med, New York, NY USA

来源：

VACCINE | 2008年 / 26卷

关键词：

Influenza virus; RNA viruses; Antigenic shift; Antigenic drift;

D O I：

10.1016/j.vaccine.2008.07.039

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The influenza viruses are characterized by segmented, negative-strand RNA genomes requiring an RNA-dependent RNA polymerase of viral origin for replication. The particular structure of the influenza virus genome and function of its viral proteins enable antigenic drift and antigenic shift. These processes result in Viruses able to evade the long-term adaptive immune responses in many hosts. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：D49 / D53

页数：5

共 48 条

[1] Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic [J].

Ahmed, Rafi ;

Oldstone, Michael B. A. ;

Palese, Peter .

NATURE IMMUNOLOGY, 2007, 8 (11) :1188-1193

[2] Evidence for segment-nonspecific packaging of the influenza A virus genome [J].

Bancroft, CT ;

Parslow, TG .

JOURNAL OF VIROLOGY, 2002, 76 (14) :7133-7139

[3] STRUCTURE OF INFLUENZA-VIRUS RNP .1. INFLUENZA-VIRUS NUCLEOPROTEIN MELTS SECONDARY STRUCTURE IN PANHANDLE RNA AND EXPOSES THE BASES TO THE SOLVENT [J].

BAUDIN, F ;

BACH, C ;

CUSACK, S ;

RUIGROK, RWH .

EMBO JOURNAL, 1994, 13 (13) :3158-3165

[4] REPLICATION OF AVIAN INFLUENZA-VIRUSES IN HUMANS [J].

BEARE, AS ;

WEBSTER, RG .

ARCHIVES OF VIROLOGY, 1991, 119 (1-2) :37-42

[5] SEQUENCE OF RNA SEGMENT-7 OF THE INFLUENZA-B VIRUS GENOME - PARTIAL AMINO-ACID HOMOLOGY BETWEEN THE MEMBRANE PROTEINS-(M1) OF INFLUENZA-A AND INFLUENZA-B VIRUSES AND CONSERVATION OF A 2ND OPEN READING FRAME [J].

BRIEDIS, DJ ;

LAMB, RA ;

CHOPPIN, PW .

VIROLOGY, 1982, 116 (02) :581-588

[6] INFLUENZA B-VIRUS GENOME - SEQUENCES AND STRUCTURAL ORGANIZATION OF RNA SEGMENT-8 AND THE MESSENGER-RNAS CODING FOR THE NS1 AND NS2 PROTEINS [J].

BRIEDIS, DJ ;

LAMB, RA .

JOURNAL OF VIROLOGY, 1982, 42 (01) :186-193

[7] A novel influenza A virus mitochondrial protein that induces cell death [J].

Chen, WS ;

Calvo, PA ;

Malide, D ;

Gibbs, J ;

Schubert, U ;

Bacik, I ;

Basta, S ;

O'Neill, R ;

Schickli, J ;

Palese, P ;

Henklein, P ;

Bennink, JR ;

Yewdell, JW .

NATURE MEDICINE, 2001, 7 (12) :1306-1312

[8] STRUCTURE OF THE CATALYTIC AND ANTIGENIC SITES IN INFLUENZA-VIRUS NEURAMINIDASE [J].

COLMAN, PM ;

VARGHESE, JN ;

LAVER, WG .

NATURE, 1983, 303 (5912) :41-44

[9] STRUCTURE OF RIBONUCLEOPROTEIN OF INFLUENZA VIRUS [J].

COMPANS, RW ;

CONTENT, J ;

DUESBERG, PH .

JOURNAL OF VIROLOGY, 1972, 10 (04) :795-&

[10] Trafficking of viral genomic RNA into and out of the nucleus: influenza, Thogoto and Borna disease viruses [J].

Cros, JF ;

Palese, P .

VIRUS RESEARCH, 2003, 95 (1-2) :3-12

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