Incompletely Excised Basal Cell Carcinoma: Residual Tumor Rates at Mohs Re-Excision

被引:14
作者
Palmer, Vanessa M. [1 ]
Wilson, Perry R. [2 ]
机构
[1] St Thomas Hosp, St Johns Inst Dermatol, London SE1 7EH, England
[2] Toowoomba Eye & Skin Clin, Toowoomba, Qld, Australia
关键词
NONMELANOMA SKIN-CANCER; SPONTANEOUS REGRESSION; SURGICAL-TREATMENT; MANAGEMENT; MARGINS; ERADICATION; CONTRIBUTE; CURETTAGE; SURGERY; AUDIT;
D O I
10.1111/dsu.12113
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background Basal cell carcinoma (BCC) is the most common skin cancer, and incompletely excised BCC is a commonly encountered clinical scenario. Objective To investigate the incidence of histologic and clinical evidence of residual BCC at Mohs micrographic surgery (MMS) for the treatment of incompletely excised BCC. Methods and Materials One hundred incompletely excised BCCs, from our practice and referred to our practice by local family doctors, treated using MMS between 2005 and 2007 were studied. Patient data included sex, age, anatomic location of tumor, histologic subtype, margin involved, initial closure and closure after MMS, and Mohs stages required for histologic clearance. Results Sixty-nine percent of incompletely excised BCCs had residual tumor at MMS re-excision, and 12% had clinically evident residual disease. Conclusion Immediate re-excision using MMS is recommended for treatment of incompletely excised BCC because the majority of cases have histologically detectable BCC. Watch and wait advice could lead to significant morbidity because recurrence may necessitate more extensive closures and costs. Long-term follow-up is recommended. It is important to conduct self-audits of incomplete excisions and follow up these patients.
引用
收藏
页码:706 / 718
页数:13
相关论文
共 50 条
[1]   A Useful Alternative Approach for the Treatment of Well-Demarcated Basal Cell Carcinoma: Surgical Excision and Margin Control with Tzanck Smear Test [J].
Baba, Mete ;
Durdu, Murat ;
Seckin, Deniz .
DERMATOLOGIC SURGERY, 2010, 36 (05) :659-664
[2]   The significance of tumor persistence after incomplete excision of basal cell carcinoma [J].
Berlin, J ;
Katz, KH ;
Helm, KF ;
Maloney, ME .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2002, 46 (04) :549-553
[3]   Margin involvement and clinical pattern of basal cell carcinoma with mixed histology [J].
Betti, R. ;
Radaelli, G. ;
Crosti, C. ;
Ghiozzi, S. ;
Moneghini, L. ;
Menni, S. .
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2012, 26 (04) :483-487
[4]   THE USE OF MOHS MICROGRAPHIC SURGERY FOR DETERMINATION OF RESIDUAL TUMOR IN INCOMPLETELY EXCISED BASAL-CELL CARCINOMA [J].
BIELEY, HC ;
KIRSNER, RS ;
REYES, BA ;
GARLAND, LD .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1992, 26 (05) :754-756
[5]   Histological evolution of recurrent basal cell carcinoma and therapeutic implications for incompletely excised lesions [J].
Boulinguez, S ;
Grison-Tabone, C ;
Lamant, L ;
Valmary, S ;
Viraben, R ;
Bonnetblanc, JM ;
Bédane, C .
BRITISH JOURNAL OF DERMATOLOGY, 2004, 151 (03) :623-626
[6]   Basal Cell Carcinoma: 10 Years of Experience [J].
Cigna, Emanuele ;
Tarallo, Mauro ;
Maruccia, Michele ;
Sorvillo, Valentina ;
Pollastrini, Alessia ;
Scuderi, Nicolo .
JOURNAL OF SKIN CANCER, 2011, 2011
[7]  
CURSON C, 1979, J CUTAN PATHOL, V6, P432, DOI 10.1111/j.1600-0560.1979.tb01166.x
[8]   Confident complete excision of lid-margin BCCs using a marginal strip: an alternative to Mohs' surgery [J].
Dhingra, Narendra ;
Gajdasty, Adam ;
Neal, Jim W. ;
Mukherjee, Achyut N. ;
Lane, Carol M. .
BRITISH JOURNAL OF OPHTHALMOLOGY, 2007, 91 (06) :794-796
[9]   Incomplete excision of basal cell carcinomas: A retrospective audit [J].
Dieu, T ;
Macleod, AM .
ANZ JOURNAL OF SURGERY, 2002, 72 (03) :219-221
[10]   Reducing the learning curve for the treatment of morphoeic (sclerosing) basal cell carcinoma of the face [J].
Erba, Paolo ;
Wettstein, Reto ;
Rieger, Ulrich M. ;
Beltraminelli, Helmut ;
Pierer, Gerhard ;
Kalbermatten, Daniel F. .
SCANDINAVIAN JOURNAL OF PLASTIC AND RECONSTRUCTIVE SURGERY AND HAND SURGERY, 2008, 42 (03) :122-126