Current situation on analysis of marine toxins

被引：11

作者：

Botana, Ana M. ^{[2
]}

Otero, Paz ^{[1
]}

Rodriguez, Paula ^{[1
]}

Alfonso, Amparo ^{[1
]}

Botana, Luis M. ^{[1
]}

机构：

[1] Univ Santiago de Compostela, Fac Vet, Sch Vet, Dept Pharmacol, Lugo 27002, Spain

[2] Univ Santiago de Compostela, Dept Analyt Chem, Lugo 27002, Spain

来源：

REVIEWS IN ANALYTICAL CHEMISTRY | 2013年 / 32卷 / 01期

关键词：

analytical standards; chromatography; marine toxins; mass spectrometry; PERFORMANCE LIQUID-CHROMATOGRAPHY; TANDEM MASS-SPECTROMETRY; PARALYTIC SHELLFISH POISONS; LINKED-IMMUNOSORBENT-ASSAY; SINGLE-LABORATORY VALIDATION; BIOSENSOR SCREENING METHOD; LC-MS/MS ANALYSIS; DOMOIC ACID; PUFFER FISH; OKADAIC ACID;

D O I：

10.1515/revac-2012-0020

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Marine toxins are a food safety concern worldwide. This review discusses current analytical methods for those toxins that are legally regulated in Europe, namely domoic acid, saxitoxin, okadaic acid, yessotoxin, pectenotoxin and azaspiracids, and all their analogues, and those that are not regularly monitored but are a threat to humans, such as tetrodotoxin, ciguatoxins and cyclic imines. Because of legislative changes that were implemented in 2011, most legally required methods are chromatographic. Saxitoxin and domoic acid are monitored by high-performance liquid chromatography with fluorescent and ultraviolet detection, respectively. All other toxins are monitored nowadays by means of chromatographic separation and mass spectrometry detection.

引用

页码：15 / 34

页数：20

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