Chemical mechanism of DNA scission by (1,10-phenanthroline)copper. Carbonyl oxygen of 5-methylenefuranone is derived from water

被引：144
作者：
Meijler, MM
Zelenko, O
Sigman, DS
机构：
[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT BIOL CHEM,LOS ANGELES,CA 90095
[2] UNIV CALIF LOS ANGELES,DEPT CHEM & BIOCHEM,INST MOL BIOL,LOS ANGELES,CA 90095
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1997年 / 119卷 / 05期
关键词：
D O I：
10.1021/ja962409n
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
[No abstract available]
引用
收藏
页码：1135 / 1136
页数：2
相关论文
共 16 条
[1]   POTASSIUM MONOPERSULFATE AND A WATER-SOLUBLE MANGANESE PORPHYRIN COMPLEX, [MN(TMPYP)](OAC)5, AS AN EFFICIENT REAGENT FOR THE OXIDATIVE CLEAVAGE OF DNA [J].
BERNADOU, J ;
PRATVIEL, G ;
BENNIS, F ;
GIRARDET, M ;
MEUNIER, B .
BIOCHEMISTRY, 1989, 28 (18) :7268-7275
[2]  
BERNADOU J, 1996, DNA RNA CLEAVERS C C, V479, P1
[3]  
GOLDBERG IH, 1996, DNA RNA CLEAVERS C C, V479, P1
[4]   NUCLEASE ACTIVITY OF 1,10-PHENANTHROLINE COPPER-ION - CHEMISTRY OF DEOXYRIBOSE OXIDATION [J].
GOYNE, TE ;
SIGMAN, DS .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (09) :2846-2848
[5]   AN IMPROVED SYNTHESIS OF PROTOANEMONIN [J].
GRUNDMANN, C ;
KOBER, E .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1955, 77 (08) :2332-2333
[6]   NUCLEASE ACTIVITY OF 1,10-PHENANTHROLINE COPPER-ION - REACTION WITH CGCGAATTCGCG AND ITS COMPLEXES WITH NETROPSIN AND ECORI [J].
KUWABARA, M ;
YOON, C ;
GOYNE, T ;
THEDERAHN, T ;
SIGMAN, DS .
BIOCHEMISTRY, 1986, 25 (23) :7401-7408
[7]   SELECTIVE ABSTRACTION OF H-2 FROM C-1' OF THE C-RESIDUE IN AGC.ICT BY THE RADICAL CENTER AT C-2 OF ACTIVATED NEOCARZINOSTATIN CHROMOPHORE - STRUCTURE OF THE DRUG DNA COMPLEX RESPONSIBLE FOR BISTRANDED LESION FORMATION [J].
MESCHWITZ, SM ;
SCHULTZ, RG ;
ASHLEY, GW ;
GOLDBERG, IH .
BIOCHEMISTRY, 1992, 31 (38) :9117-9121
[8]   DNA-BINDING PROTEINS AS SITE-SPECIFIC NUCLEASES [J].
PAN, CQ ;
LANDGRAF, R ;
SIGMAN, DS .
MOLECULAR MICROBIOLOGY, 1994, 12 (03) :335-342
[9]   OXIDATION AT CARBON-1' OF DNA DEOXYRIBOSES BY THE MN-TMPYP/KHSO5 SYSTEM RESULTS FROM A CYTOCHROME P-450-TYPE HYDROXYLATION REACTION [J].
PITIE, M ;
BERNADOU, J ;
MEUNIER, B .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (10) :2935-2936
[10]  
POPE LM, 1982, J BIOL CHEM, V257, P2121
12