Community perspectives on the ethical issues surrounding adolescent HIV vaccine trials in South Africa

被引：18

作者：

Jaspan, Heather B. ^{[1
]}

Soka, Nosiphiwo F. ^{[1
]}

Strode, Ann E. ^{[2
]}

Mathews, Catherine ^{[3
,4
]}

Mark, Daniella ^{[1
]}

Flisher, Alan J. ^{[5
,6
]}

Wood, Robin ^{[1
]}

Bekker, Linda-Gail ^{[1
]}

机构：

[1] Univ Cape Town, Desmond Tutu HIV Ctr, Inst Infect Dis & Mol Med, ZA-7700 Rondebosch, South Africa

[2] Univ KwaZulu Natal, Fac Law, Durban, South Africa

[3] Univ Cape Town, Sch Publ Hlth & Family Med, Infect Dis Epidemiol Unit, ZA-7700 Rondebosch, South Africa

[4] MRC, Hlth Syst Res Unit, Cape Town, South Africa

[5] Univ Cape Town, Div Child & Adolescent Psychiat, ZA-7700 Rondebosch, South Africa

[6] Univ Cape Town, Adolescent Hlth Res Inst, ZA-7700 Rondebosch, South Africa

来源：

VACCINE | 2008年 / 26卷 / 45期

关键词：

Adolescents; HIV vaccine trials; Community; Ethics;

D O I：

10.1016/j.vaccine.2008.08.033

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Adolescents globally are at high risk for HIV acquisition and are the targets of HIV prevention interventions such as HIV vaccines. In order to understand stakeholders' attitudes towards the ethical issues of adolescent involvement in HIV vaccine trials, we conducted focus group discussions with key members of a semi-urban, informal Cape Town community with high HIV prevalence in which HIV vaccine trials are taking place. Themes were identified from focus group transcripts by four researchers, and included necessity of guardian consent, age of independent consent, and confidentiality of in-trial medical results. In general, ethical adolescent HIV vaccine trials will be feasible in this community. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：5679 / 5683

页数：5

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