Effect of soy isoflavone supplementation on menopausal quality of life

被引：25
作者：
Amato, Paula [1 ]
Young, Ronald L. [1 ]
Steinberg, Francene M. [2 ]
Murray, Michael J. [3 ]
Lewis, Richard D. [4 ]
Cramer, Margaret A. [4 ]
Barnes, Stephen [5 ]
Ellis, Kenneth J. [6 ]
Shypailo, Roman J. [6 ]
Fraley, Joe Kennard [6 ]
Konzelmann, Karen L. [6 ]
Fischer, Joan G. [4 ]
LaSalle, Colette [2 ]
Smith, Elliot O'Brian [6 ]
Wong, William W. [6 ]
机构：
[1] Oregon Hlth & Sci Univ, Portland, OR 97239 USA
[2] Univ Calif Davis, Davis, CA 95616 USA
[3] Kaiser Fdn Res Inst, Sacramento, CA USA
[4] Univ Georgia, Athens, GA 30602 USA
[5] Univ Alabama Birmingham, Birmingham, AL USA
[6] Baylor Coll Med, Childrens Nutr Res Ctr, USDA, ARS, Houston, TX 77030 USA
来源：
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY | 2013年 / 20卷 / 04期
基金：
美国国家卫生研究院;
关键词：
Soy isoflavones; Menopause; Quality of life; RANDOMIZED CONTROLLED-TRIAL; PLACEBO-CONTROLLED TRIAL; DOUBLE-BLIND; POSTMENOPAUSAL WOMEN; HOT FLASHES; PERIMENOPAUSAL WOMEN; CLIMACTERIC SYMPTOMS; EQUOL SUPPLEMENT; JAPANESE WOMEN; MULTICENTER;
D O I：
10.1097/gme.0b013e318275025e
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective: The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women. Methods: A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire. Results: Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups. Conclusions: Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.
引用
收藏
页码：443 / 447
页数：5
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