Effect of soy isoflavone supplementation on menopausal quality of life

被引：25

作者：

Amato, Paula ^{[1
]}

Young, Ronald L. ^{[1
]}

Steinberg, Francene M. ^{[2
]}

Murray, Michael J. ^{[3
]}

Lewis, Richard D. ^{[4
]}

Cramer, Margaret A. ^{[4
]}

Barnes, Stephen ^{[5
]}

Ellis, Kenneth J. ^{[6
]}

Shypailo, Roman J. ^{[6
]}

Fraley, Joe Kennard ^{[6
]}

Konzelmann, Karen L. ^{[6
]}

Fischer, Joan G. ^{[4
]}

LaSalle, Colette ^{[2
]}

Smith, Elliot O'Brian ^{[6
]}

Wong, William W. ^{[6
]}

机构：

[1] Oregon Hlth & Sci Univ, Portland, OR 97239 USA

[2] Univ Calif Davis, Davis, CA 95616 USA

[3] Kaiser Fdn Res Inst, Sacramento, CA USA

[4] Univ Georgia, Athens, GA 30602 USA

[5] Univ Alabama Birmingham, Birmingham, AL USA

[6] Baylor Coll Med, Childrens Nutr Res Ctr, USDA, ARS, Houston, TX 77030 USA

来源：

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY | 2013年 / 20卷 / 04期

基金：

美国国家卫生研究院;

关键词：

Soy isoflavones; Menopause; Quality of life; RANDOMIZED CONTROLLED-TRIAL; PLACEBO-CONTROLLED TRIAL; DOUBLE-BLIND; POSTMENOPAUSAL WOMEN; HOT FLASHES; PERIMENOPAUSAL WOMEN; CLIMACTERIC SYMPTOMS; EQUOL SUPPLEMENT; JAPANESE WOMEN; MULTICENTER;

D O I：

10.1097/gme.0b013e318275025e

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women. Methods: A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire. Results: Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups. Conclusions: Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.

引用

页码：443 / 447

页数：5

共 34 条

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