MRI-guided targeted prostate biopsies in the diagnosis of prostate cancer: A systematic literature review

Introduction. - Advances in MRI technology for detection of prostate cancer allow targeted biopsies of suspicious areas. Material and methods. - A systematic literature review was performed on Medline (R) with the keywords "targeted", "prostate biopsy" and related articles. We studied 65 abstracts and 102 related abstracts, read 38 articles and selected 27 articles. Results. - Mental reconstruction gives way for targeted biopsies by direct MRI guidance inside the MRI, and MRI-TRUS fusion. The first option offers high precision targeting but is limited by the accessibility, cost and duration of the procedure. MRI-TRUS image fusion is a promising compromise. Cancer detection rates vary from 15 to 64%. Conclusion. - Biopsies targeting suspicious areas on MRI are promising to improve the sensitivity and performance of prostate biopsies. (C) 2012 Elsevier Masson SAS. All rights reserved.