Palladium-Mediated Heck-Type Reactions of [(Bromodifluoromethyl)sulfonyl]benzene: Synthesis of α-Alkenyl- and α-Heteroaryl-Substituted α,α-Difluoromethyl Phenyl Sulfones

被引：63
作者：
Surapanich, Nakin [1 ,2 ]
Kuhakarn, Chutima [1 ,2 ]
Pohmakotr, Manat [1 ,2 ]
Reutrakul, Vichai [1 ,2 ]
机构：
[1] Mahidol Univ, Dept Chem, Fac Sci, Bangkok 10400, Thailand
[2] Mahidol Univ, Fac Sci, Ctr Excellence Innovat Chem PERCH CIC, Bangkok 10400, Thailand
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 2012卷 / 30期
关键词：
Synthetic methods; Cross cou-pling; Heck reaction; Palladium; Fluorine; CROSS-COUPLING REACTION; CARBONYL-COMPOUNDS; RADICAL (PHENYLSULFONYL)DIFLUOROMETHYLATION; ETHYL BROMODIFLUOROACETATE; REDUCTIVE ELIMINATION; ASYMMETRIC-SYNTHESIS; EFFICIENT SYNTHESIS; ELECTRON-TRANSFER; ROOM-TEMPERATURE; HIGHLY EFFICIENT;
D O I：
10.1002/ejoc.201200613
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium-catalyzed Heck-type reactions of [(bromodifluoromethyl)sulfonyl]benzene (1) with styrene derivatives and heteroaromatic compounds successfully gave a-alkenyl- and a-heteroaryl-substituted a,a-difluoromethyl phenyl sulfones, respectively.
引用
收藏
页码：5943 / 5952
页数：10
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