Ketene acetal and spiroacetal constituents of the marine fungus Aigialus parvus BCC 5311

被引:32
作者
Vongvilai, P
Isaka, M
Kittakoop, P
Srikitikulchai, P
Kongsaeree, P
Thebtaranonth, Y
机构
[1] Mahidol Univ, Fac Sci, Dept Chem, Bangkok 10400, Thailand
[2] Natl Ctr Gneet Engn & Biotechnol, BIOTEC, Pathum Thani 12120, Thailand
来源
JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 03期
关键词
D O I
10.1021/np030344d
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Aigialone (1) and aigialospirol (2), two structurally unique compounds, were isolated from the mangrove fungus Aigialus parvus BCC 5311. The structure of the new ketene acetal 1 was elucidated by spectral analysis, and its relative stereochemistry was determined by X-ray crystallography. The stereochemistry of aigialospirol (2), elucidated by NMR spectral analysis, suggested that this compound is possibly derived from hypothemycin (3), a metabolite previously isolated from this same fungus.
引用
收藏
页码:457 / 460
页数:4
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