Ketene acetal and spiroacetal constituents of the marine fungus Aigialus parvus BCC 5311

被引：32

作者：

Vongvilai, P

Isaka, M

Kittakoop, P

Srikitikulchai, P

Kongsaeree, P

Thebtaranonth, Y

机构：

[1] Mahidol Univ, Fac Sci, Dept Chem, Bangkok 10400, Thailand

[2] Natl Ctr Gneet Engn & Biotechnol, BIOTEC, Pathum Thani 12120, Thailand

来源：

JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 03期

关键词：

D O I：

10.1021/np030344d

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Aigialone (1) and aigialospirol (2), two structurally unique compounds, were isolated from the mangrove fungus Aigialus parvus BCC 5311. The structure of the new ketene acetal 1 was elucidated by spectral analysis, and its relative stereochemistry was determined by X-ray crystallography. The stereochemistry of aigialospirol (2), elucidated by NMR spectral analysis, suggested that this compound is possibly derived from hypothemycin (3), a metabolite previously isolated from this same fungus.

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页码：457 / 460

页数：4

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