Clinical features of myomas

Myomas are the most common solid pelvic tumors in women. They are the primary indication for hysterectomy and the cause of significant morbidity from profuse menstrual bleeding and pelvic discomfort to reproductive problems. Most uterine myomas cause no symptoms. The role of uterine myomas as a possible cause of infertility is still a matter of debate. Myomas may be associated with miscarriage and obstetric complications in pregnancy. Malignant transformation of myomas is a very rare event. Several myoma-associated familial syndromes have been defined. More studies are needed to define natural clinical history of uterine myomas.