Child abuse is a serious public health problem worldwide. Although the strategies to assist and prevent it have increased, these have been insufficient. It is undeniable that social situations such as poverty, illiteracy, customs, as well as other determinants for health, mask the frequency and consequences of the victims of this medical-social-legal pathology of humanity. The knowledge of the Neurobiology involved in MI offers new fields of research to solve four neuroimmunogenetic situations and the development of tertiary prevention strategies for the problem: 1) Is it possible to specify the development of the "transgenerational replication" of the MI? 2)Can the genes involved in the genesis of the "transgenerational replication" of MI he known? 3) Can the implementation of "Epigenomics" be a possible mechanism for the study and preventive treatment of MI? 4) Is there a medicine, a food or a natural substance that can modify the response of a gene to the existence of various elements of the environment?. To understand this problems, it is essential to know the basic concepts of aggressiveness and violence of man; the neuroanatomy, neurophysiology and neurobiochemical considerations in situations of violence. The intervention of the limbic system (amygdala, hippocampus), corpus callosum and prefrontal cortex. The role of known genes that participate in the development of violence. Finally, find a medicine. a food or a natural substance that allows to modify the actions of the genes involved.