Liquid biopsy: A new avenue in pathology

被引：30

作者：

Ghosh, Ratan Kumar ^{[1
]}

Pandey, Tushar ^{[2
]}

Dey, Pranab ^{[3
]}

机构：

[1] Post Grad Inst Med Educ & Res, Dept Nephrol, Chandigarh, India

[2] Post Grad Inst Med Educ & Res, Dept Pathol, Chandigarh, India

[3] Post Grad Inst Med Educ & Res, Dept Cytol & Gynaec Pathol, Chandigarh, India

来源：

CYTOPATHOLOGY | 2019年 / 30卷 / 02期

关键词：

cell-free DNA; exosome; liquid biopsy; technology; CIRCULATING TUMOR-CELLS; PLASMA; DNA; EXOSOMES; BIOMARKERS; SERUM; BRAF;

D O I：

10.1111/cyt.12661

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Liquid biopsy is a relatively new entity. This non-invasive technique provides real-time information about a tumour. The liquid biopsy contains circulating tumour cells, cell-free DNA and exosomes. The main indications for liquid biopsy include early diagnosis, screening, detection of minimal residual disease, designing personalised treatment and predicting biological behaviour of the tumour. In this review, we discuss various aspects of liquid biopsy and compare it with conventional biopsy.

引用

页码：138 / 143

页数：6

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