Design of self-disinfecting PVC surfaces using the click chemistry

被引：25

作者：

Lafarge, Jerome ^{[1
]}

Kebir, Nasreddine ^{[1
]}

Schapman, Damien ^{[2
]}

Burel, Fabrice ^{[1
]}

机构：

[1] INSA Rouen, Lab Polymeres Biopolymeres Surfaces PBS, CNRS, UMR 6270,FR 3038, F-76801 St Etienne 9, France

[2] Univ Rouen, PRIMACEN, IFR MP 23, F-76821 Mont St Aignan 9, France

来源：

REACTIVE & FUNCTIONAL POLYMERS | 2013年 / 73卷 / 11期

关键词：

Bactericidal; Antibacterial; Surface charge density; Cationic polymers; PVC; Click chemistry; BIOLOGICALLY-ACTIVE POLYCATIONS; ANTIBACTERIAL ACTIVITY; POLY(VINYL CHLORIDE); CHEMICAL-MODIFICATION; QUATERNARY AMMONIUM; BACTERIAL ADHESION; PHOSPHONIUM SALTS; MOLECULAR-WEIGHT; BIOCIDES; COATINGS;

D O I：

10.1016/j.reactfunctpolym.2013.08.001

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Novel bactericidal PVC surfaces were developed. Cationic copolymers containing alkyne groups and quaternary ammonium or phosphonium groups were successfully synthesized and characterized. These polymers were grafted by click chemistry on PVC surfaces bearing azide groups (PVC-N3). The modified surfaces exhibited higher polarity and hydrophilicity in comparison with non grafted surfaces. Accessible surface charge densities varied from 1.1 x 10(14) to 6.5 x 10(14) charge cm(-2). In these conditions, bactericidal effects of the cationic surfaces against Escherichia coli and Staphylococcus epidermidis were evidenced by the Live and Dead fluorescent assay. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：1464 / 1472

页数：9

共 62 条

[1] Polysaccharides Coatings on Medical-Grade PVC: A Probe into Surface Characteristics and the Extent of Bacterial Adhesion [J].

Asadinezhad, Ahmad ;

Novak, Igor ;

Lehocky, Marian ;

Bilek, Frantisek ;

Vesel, Alenka ;

Junkar, Ita ;

Saha, Petr ;

Popelka, Anton .

MOLECULES, 2010, 15 (02) :1007-1027

[2] Chemical modification of poly(vinyl chloride) resin using poly(ethylene glycol) to improve blood compatibility [J].

Balakrishnan, B ;

Kumar, DS ;

Yoshida, Y ;

Jayakrishnan, A .

BIOMATERIALS, 2005, 26 (17) :3495-3502

[3] Inhibition of bacterial adhesion on PVC endotracheal tubes by RF-oxygen glow discharge, sodium hydroxide and silver nitrate treatments [J].

Balazs, DJ ;

Triandafillu, K ;

Wood, P ;

Chevolot, Y ;

van Delden, C ;

Harms, H ;

Hollenstein, C ;

Mathieu, HJ .

BIOMATERIALS, 2004, 25 (11) :2139-2151

[4] Plasma-assisted surface modification of organic biopolymers to prevent bacterial attachment [J].

Bazaka, Kateryna ;

Jacob, Mohan V. ;

Crawford, Russell J. ;

Ivanova, Elena P. .

ACTA BIOMATERIALIA, 2011, 7 (05) :2015-2028

[5] Facile grafting of bioactive cellulose derivatives onto PVC surfaces [J].

Bigot, Sandra ;

Louarn, Guy ;

Kebir, Nasreddine ;

Burel, Fabrice .

APPLIED SURFACE SCIENCE, 2013, 283 :411-416

[6] A new, simple approach to confer permanent antimicrobial properties to hydroxylated surfaces by surface functionalization [J].

Bouloussa, Othman ;

Rondelez, Francis ;

Semetey, Vincent .

CHEMICAL COMMUNICATIONS, 2008, (08) :951-953

[7] Surface functionalization technique for conferring antibacterial properties to polymeric and cellulosic surfaces [J].

Cen, L ;

Neoh, KG ;

Kang, ET .

LANGMUIR, 2003, 19 (24) :10295-10303

[8] The synthesis, characterization and antibacterial activity of quaternized poly(2,6-dimethyl-1,4-phenylene oxide)s modified with ammonium and phosphonium salts [J].

Chang, Hsin-I ;

Yang, Ming-Syun ;

Liang, Mong .

REACTIVE & FUNCTIONAL POLYMERS, 2010, 70 (12) :944-950

[9] Designing N-halamine based antibacterial surface on polymers: Fabrication, characterization, and biocidal functions [J].

Chen, Yong ;

Han, Qiuxia .

APPLIED SURFACE SCIENCE, 2011, 257 (14) :6034-6039

[10] Mixed azide-terminated monolayers: A platform for modifying electrode surfaces [J].

Collman, JP ;

Devaraj, NK ;

Eberspacher, TPA ;

Chidsey, CED .

LANGMUIR, 2006, 22 (06) :2457-2464

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