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Morphological analysis and cell viability on diamond-like carbon films containing nanocrystalline diamond particles
被引:7
|作者:
Almeida, C. N.
[1
]
Ramos, B. C.
[1
]
Da-Silva, N. S.
[2
]
Pacheco-Soares, C.
[2
]
Trava-Airoldi, V. J.
[3
]
Lobo, A. O.
[1
]
Marciano, F. R.
[1
]
机构:
[1] Univ Vale do Paraiba Univap, Lab Biomed Nanotechnol NanoBio, BR-12244000 Sao Jose Dos Campos, SP, Brazil
[2] Univ Vale do Paraiba Univap, Lab Biol Celular & Tecidual, BR-12244000 Sao Jose Dos Campos, SP, Brazil
[3] Inst Nacl Pesquisas Espaciais INPE, Associated Lab Sensors & Mat, BR-12227010 Sao Jose Dos Campos, SP, Brazil
基金:
巴西圣保罗研究基金会;
关键词:
Diamond-like carbon;
Crystalline diamond nanoparticles;
Cell viability;
Fibroblasts;
SURFACE FREE-ENERGY;
AMORPHOUS-CARBON;
ION-IMPLANTATION;
POLYMER SURFACES;
PLASMA IMMERSION;
CYTO-TOXICITY;
DLC COATINGS;
THIN-FILM;
DEPOSITION;
FRICTION;
D O I:
10.1016/j.apsusc.2012.12.122
中图分类号:
O64 [物理化学(理论化学)、化学物理学];
学科分类号:
070304 ;
081704 ;
摘要:
The coating of orthopedic prostheses with diamond like-carbon (DLC) has been actively studied in the past years, in order to improve mechanical, tribological properties and promote the material's biocompatibility. Recently, the incorporation of crystalline diamond nanoparticles into the DLC film has shown effective in combating electrochemical corrosion in acidic medias. This study examines the material's biocompatibility through testing by LDH release and MTT, on in vitro fibroblasts; using different concentrations of diamond nanoparticles incorporated into the DLC film. Propounding its potential use in orthopedics in order to increase the corrosion resistance of prostheses and improve their relationship with the biological environment. (C) 2013 Elsevier B.V. All rights reserved.
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页码:258 / 263
页数:6
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