Low Serum Insulin-Like Growth Factor 1 Potentiates Atherosclerotic Plaque Development in APOE-/- Mice: Potential Mechanism of Accelerated Atherosclerosis in Aging

被引：0
|
作者：
Shai, Shaw-Yung [1 ]
Kelly, James
Higashi, Yusuke [1 ]
Sukhanov, Sergiy [1 ]
Delafontaine, Patrice [1 ]
机构：
[1] Tulane Univ, Sch Med, Inst Heart & Vasc, New Orleans, LA 70112 USA
来源：
FASEB JOURNAL | 2009年 / 23卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
357.9
引用
收藏
页数：1
相关论文
共 50 条
  • [31] Expression of insulin-like growth factor-1 in vascular smooth muscle cells is associated with oxidized LDL in human atherosclerotic plaque
    Okura, Y
    Itabe, H
    Ono, K
    Nakashima, Y
    Saku, K
    ATHEROSCLEROSIS SUPPLEMENTS, 2003, 4 (02) : 63 - 63
  • [32] INSULIN-LIKE GROWTH FACTOR I (IGF-1) SUPPRESSED CHEMOKINES AND MONOCYTES RECRUITMENT INTO ATHEROSCLEROTIC PLAQUE: NOVEL MECHANISM CONTRIBUTING TO IGF-1-INDUCED ATHEROPROTECTION
    Sukhanov, S.
    Snarski, P.
    Higashi, Y.
    Delafontaine, P.
    JOURNAL OF INVESTIGATIVE MEDICINE, 2017, 65 (02) : 397 - 397
  • [33] Insulin-like growth factor 1 prevents atherosclerosis progression in aged apolipoprotein E-deficient mice.
    Higashi, Y.
    Sukhanov, S.
    Shai, S.-Y.
    Titterington, J.
    Delafontaine, P.
    JOURNAL OF INVESTIGATIVE MEDICINE, 2007, 55 (01) : S279 - S279
  • [34] Targeting insulin-like growth factor 1 receptor restricts development and severity of secondary lymphedema in mice
    Yuan, Yinan
    Levy, Sidney M.
    Yeo, Yong Qiang
    Shayan, Ramin
    Karnezis, Tara
    Stacker, Steven A.
    Achen, Marc G.
    ISCIENCE, 2025, 28 (03)
  • [35] Insulin-like growth factor-I reduces inflammatory responses, suppresses oxidative stress and decreases atherosclerosis progression in ApoE-deficient mice
    Sukhanov, S.
    Higashi, Y.
    Shai, S.
    Vaughn, C.
    Titterington, J.
    Delafontaine, P.
    JOURNAL OF INVESTIGATIVE MEDICINE, 2008, 56 (01) : 455 - 456
  • [36] Insulin-like growth factor-I reduces inflammatory responses, suppresses oxidative stress and decreases atherosclerosis progression in apoE-deficient mice
    Sukhanov, Sergiy
    Higashi, Yusuke
    Shai, Shaw-Yung
    Vaughn, Charlotte
    Titterington, Jane
    Delafontaine, Patrick
    CIRCULATION, 2007, 116 (16) : 246 - 246
  • [37] Monocyte/Macrophage Specific Knockout of Insulin-like Growth Factor-1 Receptor Promotes Atherosclerosis and Induces an Unstable Plaque Phenotype
    Higashi, Yusuke
    Shai, Shaw-yung
    Sukhanov, Sergiy
    Kim, Catherine
    Delafontaine, Patrice
    CIRCULATION, 2011, 124 (21)
  • [38] Potential use of serum insulin-like growth factor 1 and E-cadherin as biomarkers of colorectal cancer
    Zeljkovic, A.
    Mihajlovic, M.
    Stefanovic, A.
    Zeljkovic, D.
    Trifunovic, B.
    Miljkovic, M.
    Spasojevic-Kalimanovska, V.
    Vekic, J.
    COLORECTAL DISEASE, 2020, 22 (12) : 2078 - 2086
  • [39] INSULIN-LIKE GROWTH FACTOR INCREASES COLLAGEN-1α AND CONTRACTILE PROTEIN EXPRESSION IN VASCULAR SMOOTH MUSCLE: MECHANISMS OF ATHEROSCLEROTIC PLAQUE STABILIZATION
    Blackstock, C.
    Higashi, Y.
    Sukhanov, S.
    Delafontaine, P.
    JOURNAL OF INVESTIGATIVE MEDICINE, 2013, 61 (02) : 461 - 461
  • [40] Deficiency for Smooth Muscle-specific Insulin-like Growth Factor I (IGF-1) Receptor Increases Atherosclerotic Plaque Size and Promotes Plaque Destabilization
    Sukhanov, Sergiy
    Higashi, Yusuke
    Snarski, Patricia
    Delafontaine, Patrick
    FASEB JOURNAL, 2016, 30
12345