Role of Omega-3 Polyunsaturated Fatty Acids in Mental Health-Studies from Japan

被引：11

作者：

Hamazaki, Kei ^{[1
]}

机构：

[1] Univ Toyama, Fac Med, Dept Publ Hlth, 2630 Sugitani, Toyama, Toyama 9300194, Japan

来源：

JOURNAL OF OLEO SCIENCE | 2019年 / 68卷 / 06期

关键词：

omega-3 polyunsaturated fatty acids; depression; epidemiological studies; clinical trials; DEPRESSIVE SYMPTOMS; DOCOSAHEXAENOIC ACID; PERINATAL DEPRESSION; DIETARY-INTAKE; POSTPARTUM DEPRESSION; NEUROTROPHIC FACTOR; FISH CONSUMPTION; DOUBLE-BLIND; OMEGA-3-FATTY-ACIDS; SUPPLEMENTATION;

D O I：

10.5650/jos.ess19008

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Omega-3 polyunsaturated fatty acids is a generic term that encompasses eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are abundant in fish, and alpha-linolenic acid, which is abundant in perilla oil. These fatty acids became well known following an epidemiological study conducted in Greenland about 50 years ago. EPA formulations, with their putative prophylactic effect against cardiovascular disease, first became clinically available in the 1990s in Japan. There were reports of their association with mental health, especially depression, and from around the year 2000 several epidemiological studies and clinical trials were conducted. This article introduces the epidemiological studies and clinical trials conducted in Japan and the knowledge gained.

引用

页码：511 / 515

页数：5

共 40 条

[1]

[Anonymous], NAT HLTH NUTR SURV

[2]

Delion S, 1996, J NEUROCHEM, V66, P1582

[3]

FEHILY A M A, 1981, Neurochemistry International, V3, P37, DOI 10.1016/0197-0186(81)90047-4

[4] Omega-3 fatty acids and supportive psychotherapy for perinatal depression: A randomized placebo-controlled study [J].

Freeman, Marlene P. ;

Davis, Melinda ;

Sinha, Pniti ;

Wisner, Katherine L. ;

Hibbeln, Joseph R. ;

Gelenberg, Alan J. .

JOURNAL OF AFFECTIVE DISORDERS, 2008, 110 (1-2) :142-148

[5] Omega-3 fatty acids: Evidence basis for treatment and future research in psychiatry [J].

Freeman, Marlene P. ;

Hibbeln, Joseph R. ;

Wisner, Katherine L. ;

Davis, John M. ;

Mischoulon, David ;

Peet, Malcolm ;

Keck, Paul E., Jr. ;

Mayangell, Lauren B. ;

Richardson, Alexandra J. ;

Lake, James ;

Stoll, Andrew L. .

JOURNAL OF CLINICAL PSYCHIATRY, 2006, 67 (12) :1954-1967

[6] Fish consumption and depressive symptoms in undergraduate students: A cross-sectional analysis [J].

Hamazaki, K. ;

Natori, T. ;

Kurihara, S. ;

Murata, N. ;

Cui, Z-G. ;

Kigawa, M. ;

Morozumi, R. ;

Inadera, H. .

EUROPEAN PSYCHIATRY, 2015, 30 (08) :983-987

[7] Dietary intake of fish and n-3 polyunsaturated fatty acids and risks of perinatal depression: The Japan Environment and Children's Study (JECS) [J].

Hamazaki, Kei ;

Takamori, Ayako ;

Tsuchida, Akiko ;

Kigawa, Mika ;

Tanaka, Tomomi ;

Ito, Mika ;

Adachi, Yuichi ;

Saito, Shigeru ;

Origasa, Hideki ;

Inadera, Hidekuni ;

Kishi, Reiko ;

Yaegashi, Nobuo ;

Hashimoto, Koichi ;

Mori, Chisato ;

Ito, Shuichi ;

Yamagata, Zentaro ;

Inadera, Hidekuni ;

Kamijima, Michihiro ;

Nakayama, Takeo ;

Iso, Hiroyasu ;

Shima, Masayuki ;

Hirooka, Yasuaki ;

Suganuma, Narufumi ;

Kusuhara, Koichi ;

Katoh, Takahiko .

JOURNAL OF PSYCHIATRIC RESEARCH, 2018, 98 :9-16

[8] Brain-derived neurotrophic factor as a biomarker for mood disorders: An historical overview and future directions [J].

Hashimoto, Kenji .

PSYCHIATRY AND CLINICAL NEUROSCIENCES, 2010, 64 (04) :341-357

[9] Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects, and early- and late-onset alcoholics [J].

Hibbeln, JR ;

Linnoila, M ;

Umhau, JC ;

Rawlings, R ;

George, DT ;

Salem, N .

BIOLOGICAL PSYCHIATRY, 1998, 44 (04) :235-242

[10] Fish consumption and major depression [J].

Hibbeln, JR .

LANCET, 1998, 351 (9110) :1213-1213

← 1 2 3 4 →