Short-term outcomes of open versus laparoscopic surgery in elderly patients with colorectal cancer

被引:25
作者
Nishikawa, Takeshi [1 ]
Ishihara, Soichiro [1 ]
Hata, Keisuke [1 ]
Murono, Koji [1 ]
Yasuda, Koji [1 ]
Otani, Kensuke [1 ]
Tanaka, Toshiaki [1 ]
Kiyomatsu, Tomomichi [1 ]
Kawai, Kazushige [1 ]
Nozawa, Hiroaki [1 ]
Yamaguchi, Hironori [1 ]
Watanabe, Toshiaki [1 ]
机构
[1] Univ Tokyo, Dept Surg Oncol, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan
来源
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES | 2016年 / 30卷 / 12期
关键词
Laparoscopic surgery; Open surgery; Colorectal cancer; Elderly patients; LOW-RECTAL-CANCER; OPEN RESECTION; RANDOMIZED-TRIAL; OPEN-LABEL; CARCINOMA; EFFICACY;
D O I
10.1007/s00464-016-4921-y
中图分类号
R61 [外科手术学];
学科分类号
摘要
Along with an aging society, the number of elderly patients with colorectal cancer treated with a surgical modality has gradually increased. Our purpose is to verify the safety and effectiveness of laparoscopic surgery for the treatment of colorectal cancer in elderly patients. We compared the short-term outcomes of open versus laparoscopic surgery in patients aged 80 years or older with colorectal cancer between 2007 and 2014. Of 150 elderly colorectal patients, 62 patients received laparoscopic surgery, and 88 patients, open surgery. In the laparoscopic surgery group, two patients were converted to open surgery due to extensive adhesion. The amount of blood loss was smaller in patients treated with laparoscopic surgery than those with open surgery (44.0 +/- 86.5 vs. 329.9 +/- 482.1 ml, P < 0.01). In the laparoscopic surgery group, days until oral intake (5.3 +/- 1.9 vs. 7.0 +/- 3.0 days, P < 0.01) and hospital stay (17.2 +/- 6.8 vs. 22.0 +/- 14.0 days, P < 0.01) were shorter. Morbidity (30.6 vs. 42.0 %) and mortality (1.6 vs. 1.1 %) in laparoscopic and open surgery groups were similar. Laparoscopic surgery in elderly patients with colorectal cancer was a safe and less invasive alternative to open surgery, with less blood loss and shorter hospital stay.
引用
收藏
页码:5550 / 5557
页数:8
相关论文
共 26 条
  • [1] A Randomized Trial of Laparoscopic versus Open Surgery for Rectal Cancer
    Bonjer, H. Jaap
    Deijen, Charlotte L.
    Abis, Gabor A.
    Cuesta, Miguel A.
    van der Pas, Martijn H. G. M.
    de lange-de Klerk, Elly S. M.
    Lacy, Antonio M.
    Bemelman, Willem A.
    Andersson, John
    Angenete, Eva
    Rosenberg, Jacob
    Fuerst, Alois
    Haglind, Eva
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (14) : 1324 - 1332
  • [2] Bonjer HJ, 2009, LANCET ONCOL, V10, P44, DOI 10.1016/S1470-2045(08)70310-3
  • [3] Laparoscopic surgery versus open surgery for colon cancer:: short-term outcomes of a randomised trial
    Bonjer, HJ
    Haglind, E
    Jeekel, I
    Kazemier, G
    Páhlman, L
    Hop, WCJ
    Veldkamp, R
    Kuhry, E
    Haglind, E
    Pahlman, L
    Cuesta, MA
    Msika, S
    Morino, M
    Lacy, A
    Jeekel, I
    [J]. LANCET ONCOLOGY, 2005, 6 (07) : 477 - 484
  • [4] Laparoscopic colectomy for transverse colon carcinoma: a surgical challenge but oncologically feasible
    Fernandez-Cebrian, J. M.
    Gil Yonte, P.
    Jimenez-Toscano, M.
    Vega, L.
    Ochando, F.
    [J]. COLORECTAL DISEASE, 2013, 15 (02) : E79 - E83
  • [5] Laparoscopic colectomy for cancer is not inferior to open surgery based on 5-year data from the COST Study Group Trial
    Fleshman, James
    Sargent, Daniel J.
    Green, Erin
    Anvari, Mehran
    Stryker, Steven J.
    Beart, Robert W., Jr.
    Hellinger, Michael
    Flanagan, Richard, Jr.
    Peters, Walter
    Nelson, Heidi
    [J]. ANNALS OF SURGERY, 2007, 246 (04) : 655 - 664
  • [6] Short-term results of a randomized study between laparoscopic and open surgery in elderly colorectal cancer patients
    Fujii, Shoichi
    Ishibe, Atsushi
    Ota, Mitsuyoshi
    Yamagishi, Shigeru
    Watanabe, Kazuteru
    Watanabe, Jun
    Kanazawa, Amane
    Ichikawa, Yasushi
    Oba, Mari
    Morita, Satoshi
    Hashiguchi, Yojiro
    Kunisaki, Chikara
    Endo, Itaru
    [J]. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2014, 28 (02): : 466 - 476
  • [7] Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial
    Guillou, PJ
    Quirke, P
    Thorpe, H
    Walker, J
    Jayne, DG
    Smith, AMH
    Heath, RM
    Brown, JM
    [J]. LANCET, 2005, 365 (9472) : 1718 - 1726
  • [8] Efficacy and safety of laparoscopic surgery in elderly patients with colorectal cancer
    Inoue, Yasuhiro
    Kawamoto, Aya
    Okugawa, Yoshinaga
    Hiro, Junichiro
    Saigusa, Susumu
    Toiyama, Yuji
    Araki, Toshimitsu
    Tanaka, Koji
    Mohri, Yasuhiko
    Kusunoki, Masato
    [J]. MOLECULAR AND CLINICAL ONCOLOGY, 2015, 3 (04) : 897 - 901
  • [9] Jacobs M, 1991, Surg Laparosc Endosc, V1, P144
  • [10] Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC trial group
    Jayne, David G.
    Guillou, Pierre J.
    Thorpe, Helen
    Quirke, Philip
    Copeland, Joanne
    Smith, Adrian M. H.
    Heath, Richard M.
    Brown, Julia M.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (21) : 3061 - 3068