Tumor enucleation for small renal masses

被引:16
作者
Laryngakis, Nicholas A. [1 ]
Guzzo, Thomas J. [1 ]
机构
[1] Hosp Univ Penn, Perelman Ctr Adv Med W Pavil, Div Urol, Dept Surg, Philadelphia, PA 19104 USA
关键词
enucleation; local recurrence; nephron-sparing surgery; partial nephrectomy; renal cell carcinoma; NEPHRON-SPARING SURGERY; CHRONIC KIDNEY-DISEASE; CELL CARCINOMA; PARTIAL NEPHRECTOMY; RADICAL NEPHRECTOMY; SURGICAL ENUCLEATION; YAG LASER; MARGIN; CANCER; PROGRESSION;
D O I
10.1097/MOU.0b013e3283551f84
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review The incidence of renal cell carcinoma and the detection of incidental small renal masses are rising. Urologists are faced with difficult management decisions on how to treat patients with small renal masses. Traditionally, the treatment of suspicious renal masses was radical nephrectomy. However, nephron-sparing surgery is the standard of care, when possible, because of the risk of renal insufficiency associated with radical nephrectomy. Recent findings A large breadth of data have shown that partial nephrectomy has equivalent oncologic outcomes compared to radical nephrectomy. Recently, attempts to further spare renal parenchyma and perform nephron-sparing surgery in anatomically difficult scenarios have led to the development of the enucleation technique. Enucleation is performed by following the natural plane between the peritumor pseudocapsule and the renal parenchyma. This emerging technique was met with skepticism and concern for incomplete tumor removal. However, studies comparing enucleation and partial nephrectomy to date have revealed equivalent oncologic outcomes. Summary There has been a greater acceptance of tumor enucleation as a safe alternative for renal masses which are locally confined on preoperative imaging, easily delineated intraoperatively, and do not appear to grossly invade beyond the pseudocapsule.
引用
收藏
页码:365 / 371
页数:7
相关论文
共 45 条
  • [1] Elective partial nephrectomy is equivalent to radical nephrectomy in patients with clinical T1 renal cell carcinoma: results of a retrospective, comparative, multi-institutional study
    Antonelli, Alessandro
    Ficarra, Vincenzo
    Bertini, Roberto
    Carini, Marco
    Carmignani, Giorgio
    Corti, Serena
    Longo, Nicola
    Martorana, Giuseppe
    Minervini, Andrea
    Mirone, Vincenzo
    Novara, Giacomo
    Serni, Sergio
    Simeone, Claudio
    Simonato, Alchiede
    Siracusano, Salvatore
    Volpe, Alessandro
    Zattoni, Filiberto
    Cunico, Sergio Cosciani
    [J]. BJU INTERNATIONAL, 2012, 109 (07) : 1013 - 1018
  • [2] Survival after partial and radical nephrectomy for the treatment of stage T1bN0M0 renal cell carcinoma (RCC) in the USA: a propensity scoring approach
    Badalato, Gina M.
    Kates, Max
    Wisnivesky, Juan P.
    Choudhury, Arindam Roy
    McKiernan, James M.
    [J]. BJU INTERNATIONAL, 2012, 109 (10) : 1457 - 1462
  • [3] EFFICACY AND SAFETY OF THE ND - YAG LASER IN CANINE PARTIAL NEPHRECTOMY
    BENDEREV, TV
    SCHAEFFER, AJ
    [J]. JOURNAL OF UROLOGY, 1985, 133 (06) : 1108 - 1111
  • [4] Impact of resection margin status after nephron-sparing surgery for renal cell carcinoma
    Berdjis, Navid
    Hakenberg, Oliver W.
    Zastrow, Stefan
    Oehlschlaeger, Sven
    Novotny, Vladimir
    Wirth, Manfred P.
    [J]. BJU INTERNATIONAL, 2006, 97 (06) : 1208 - 1210
  • [5] EXSITU STUDY OF THE EFFECTIVENESS OF ENUCLEATION IN PATIENTS WITH RENAL-CELL CARCINOMA
    BLACKLEY, SK
    LADAGA, L
    WOOLFITT, RA
    SCHELLHAMMER, PF
    [J]. JOURNAL OF UROLOGY, 1988, 140 (01) : 6 - 10
  • [6] Canter D, 2011, UROLOGY, V77, P781, DOI 10.1016/j.urology.2010.11.050
  • [7] Simple enucleation for the treatment of renal cell carcinoma between 4 and 7 cm in greatest dimension: Progression and long-term survival
    Carini, M
    Minervini, A
    Lapini, A
    Masieri, L
    Serni, S
    [J]. JOURNAL OF UROLOGY, 2006, 175 (06) : 2022 - 2026
  • [8] Simple enucleation for the treatment of PT1a renal cell carcinoma: Our 20-year experience
    Carini, Marco
    Minervini, Andrea
    Masieri, Lorenzo
    Lapini, Alberto
    Serni, Sergio
    [J]. EUROPEAN UROLOGY, 2006, 50 (06) : 1263 - 1271
  • [9] Prognostic importance of resection margin width after nephron-sparing surgery for renal cell carcinoma
    Castilla, EA
    Liou, LS
    Abrahams, NA
    Fergany, A
    Rybicki, LA
    Myles, J
    Novick, AC
    [J]. UROLOGY, 2002, 60 (06) : 993 - 997
  • [10] Rising incidence of renal cell cancer in the United States
    Chow, WH
    Devesa, SS
    Warren, JL
    Fraumeni, JF
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 281 (17): : 1628 - 1631