Cytotoxic activity of neo-clerodane diterpenoids

被引：10

作者：

Gordaliza, M ^{[1
]}

delCorral, JMM ^{[1
]}

delaPuente, ML ^{[1
]}

GarciaGravalos, MD ^{[1
]}

SanFeliciano, A ^{[1
]}

机构：

[1] PHARMAMAR SA,E-28760 TRES CANTOS,MADRID,SPAIN

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 13期

关键词：

D O I：

10.1016/S0960-894X(97)00277-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Several neo-clerodane diterpenoids isolated from extracts of roots and aerial parts of Linaria saxatilis var. glutinosa, as well as some semisynthetic derivatives, exhibited in vitro growth inhibition against different neoplastic cell cultures. A number of substances showed IC50 values under 1 mu M. (C) 1997 Elsevier Science Ltd.

引用

页码：1649 / 1654

页数：6

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